Inducible ablation of CD11c+ cells to determine their role in skin wound repair

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Inducible ablation of CD11c+ cells to determine their role in skin wound repair. / Li, Zhi; Lamb, Rebecca; Coles, Mark; Bennette, Clare; Ambler, Carrie.

In: Immunology, 27.01.2021.

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Li, Zhi ; Lamb, Rebecca ; Coles, Mark ; Bennette, Clare ; Ambler, Carrie. / Inducible ablation of CD11c+ cells to determine their role in skin wound repair. In: Immunology. 2021.

Bibtex

@article{095b04dfc1a24cc1abe90e81049ed095,
title = "Inducible ablation of CD11c+ cells to determine their role in skin wound repair",
abstract = "Summary: Whether resident and recruited myeloid cells may impair or aid healing of acute skin wounds remains a debated question. To begin to address this, we examined the importance of CD11c+ myeloid cells in the early activation of skin wound repair. We find that an absence of CD11c+ cells delays wound closure and epidermal proliferation, likely due to defects in the activation of the IL‐23‐IL‐22 axis that is required for wound healing.",
keywords = "CD11c, dendritic cells, Langerhans cells, skin, wound repair",
author = "Zhi Li and Rebecca Lamb and Mark Coles and Clare Bennette and Carrie Ambler",
year = "2021",
month = jan,
day = "27",
doi = "10.1111/imm.13312",
language = "English",
journal = "Immunology",
issn = "0019-2805",
publisher = "Wiley",

}

RIS

TY - JOUR

T1 - Inducible ablation of CD11c+ cells to determine their role in skin wound repair

AU - Li, Zhi

AU - Lamb, Rebecca

AU - Coles, Mark

AU - Bennette, Clare

AU - Ambler, Carrie

PY - 2021/1/27

Y1 - 2021/1/27

N2 - Summary: Whether resident and recruited myeloid cells may impair or aid healing of acute skin wounds remains a debated question. To begin to address this, we examined the importance of CD11c+ myeloid cells in the early activation of skin wound repair. We find that an absence of CD11c+ cells delays wound closure and epidermal proliferation, likely due to defects in the activation of the IL‐23‐IL‐22 axis that is required for wound healing.

AB - Summary: Whether resident and recruited myeloid cells may impair or aid healing of acute skin wounds remains a debated question. To begin to address this, we examined the importance of CD11c+ myeloid cells in the early activation of skin wound repair. We find that an absence of CD11c+ cells delays wound closure and epidermal proliferation, likely due to defects in the activation of the IL‐23‐IL‐22 axis that is required for wound healing.

KW - CD11c

KW - dendritic cells

KW - Langerhans cells

KW - skin

KW - wound repair

U2 - 10.1111/imm.13312

DO - 10.1111/imm.13312

M3 - Letter

JO - Immunology

JF - Immunology

SN - 0019-2805

ER -