Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis

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@article{e7467b4738af4626bdf3f905c93dadee,
title = "Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis",
abstract = "BACKGROUND AND OBJECTIVES: Low cardiorespiratory fitness (CRF) is a significant predictor of cardiovascular disease (CVD), and interventions aiming at increasing CRF are known to reduce CVD risk. The effects of such interventions on CVD risk have not been studied in patients with rheumatoid arthritis (RA). METHODS: 40 age, gender, body mass index (BMI) and disease duration matched RA patients were allocated to either an exercise (receiving 6 months individualised aerobic and resistance high intensity exercise intervention, three times per week), or control (receiving advice on exercise benefits and lifestyle changes) arm. Participants were assessed at baseline, 3 and 6 months for aerobic capacity (VO(2)max), individual CVD risk factors (blood pressure, lipids, insulin resistance, body composition), 10-year CVD event probability and RA characteristics (C-reactive protein (CRP), Disease Activity Score 28 (DAS28) and Health Assessment Questionnaire (HAQ)). RESULTS: There were no differences between groups at baseline in any of the assessed variables. VO(2)max (p=0.001), blood pressure (systolic: p",
author = "Antonios Stavropoulos-Kalinoglou and Metsios, {Giorgos S} and {Veldhuijzen van Zanten}, {Jet JCS} and Peter Nightingale and Kitas, {George D} and Yiannis Koutedakis",
year = "2012",
month = nov,
day = "15",
doi = "10.1136/annrheumdis-2012-202075",
language = "English",
journal = "Annals of the Rheumatic Diseases",
issn = "0003-4967",
publisher = "BMJ Publishing Group",

}

RIS

TY - JOUR

T1 - Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis

AU - Stavropoulos-Kalinoglou, Antonios

AU - Metsios, Giorgos S

AU - Veldhuijzen van Zanten, Jet JCS

AU - Nightingale, Peter

AU - Kitas, George D

AU - Koutedakis, Yiannis

PY - 2012/11/15

Y1 - 2012/11/15

N2 - BACKGROUND AND OBJECTIVES: Low cardiorespiratory fitness (CRF) is a significant predictor of cardiovascular disease (CVD), and interventions aiming at increasing CRF are known to reduce CVD risk. The effects of such interventions on CVD risk have not been studied in patients with rheumatoid arthritis (RA). METHODS: 40 age, gender, body mass index (BMI) and disease duration matched RA patients were allocated to either an exercise (receiving 6 months individualised aerobic and resistance high intensity exercise intervention, three times per week), or control (receiving advice on exercise benefits and lifestyle changes) arm. Participants were assessed at baseline, 3 and 6 months for aerobic capacity (VO(2)max), individual CVD risk factors (blood pressure, lipids, insulin resistance, body composition), 10-year CVD event probability and RA characteristics (C-reactive protein (CRP), Disease Activity Score 28 (DAS28) and Health Assessment Questionnaire (HAQ)). RESULTS: There were no differences between groups at baseline in any of the assessed variables. VO(2)max (p=0.001), blood pressure (systolic: p

AB - BACKGROUND AND OBJECTIVES: Low cardiorespiratory fitness (CRF) is a significant predictor of cardiovascular disease (CVD), and interventions aiming at increasing CRF are known to reduce CVD risk. The effects of such interventions on CVD risk have not been studied in patients with rheumatoid arthritis (RA). METHODS: 40 age, gender, body mass index (BMI) and disease duration matched RA patients were allocated to either an exercise (receiving 6 months individualised aerobic and resistance high intensity exercise intervention, three times per week), or control (receiving advice on exercise benefits and lifestyle changes) arm. Participants were assessed at baseline, 3 and 6 months for aerobic capacity (VO(2)max), individual CVD risk factors (blood pressure, lipids, insulin resistance, body composition), 10-year CVD event probability and RA characteristics (C-reactive protein (CRP), Disease Activity Score 28 (DAS28) and Health Assessment Questionnaire (HAQ)). RESULTS: There were no differences between groups at baseline in any of the assessed variables. VO(2)max (p=0.001), blood pressure (systolic: p

U2 - 10.1136/annrheumdis-2012-202075

DO - 10.1136/annrheumdis-2012-202075

M3 - Article

C2 - 23155222

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

SN - 0003-4967

ER -