Abstract
Homozygous sickle cell disease (SCD) is characterised by increased soluble P-selectin (sP-selectin), suggesting increased platelet activation, and high non-transferrin-bound iron (NTBI), reflecting iron overload, possibly due to blood transfusion. Hypothesising a relationship between these processes, we measured both markers in 40 SCD patients and 40 age/gender/race-matched controls, finding increased levels of each marker in the patients (both P
| Original language | English |
|---|---|
| Pages (from-to) | 124-6 |
| Number of pages | 3 |
| Journal | British journal of biomedical science |
| Volume | 64 |
| Issue number | 3 |
| Publication status | Published - 1 Jan 2007 |