Impaired inhibitory processing: a new therapeutic target for autism and psychosis?
Research output: Contribution to journal › Article › peer-review
Colleges, School and Institutes
- Psychiatry and Youth Mental Health. Institute for Mental Health
- Radboud Universiteit
- Edgbaston Physiotherapy Clinic
- University of Oxford
- BIRMINGHAM UNIVERSITY
- University College Dublin
In the healthy brain, homeostatic balance between excitation and inhibition maintains neural stability. Reduced inhibition may explain shared symptoms observed in autism and psychosis. Here we review evidence suggesting that altered levels of gamma-aminobutyric acid (GABA) may underlie both disorders, providing a potential cross-diagnostic therapeutic target.
|Number of pages||4|
|Journal||British Journal of Psychiatry|
|Publication status||E-pub ahead of print - 23 Oct 2020|