Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity

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Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity. / Rowe, Martin; Zuo, Jianmin.

In: Microbes and Infection, Vol. 12, No. 3, 01.03.2010, p. 173-181.

Research output: Contribution to journalReview articlepeer-review

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@article{b50c319c4b9946dab0cf66c6a16cd043,
title = "Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity",
abstract = "Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation",
keywords = "Immune-evasion, Tumour virus, Epstein-Barr virus, Herpesvirus, Immune response, Antigen presentation",
author = "Martin Rowe and Jianmin Zuo",
year = "2010",
month = mar,
day = "1",
doi = "10.1016/j.micinf.2009.12.001",
language = "English",
volume = "12",
pages = "173--181",
journal = "Microbes and Infection",
issn = "1286-4579",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity

AU - Rowe, Martin

AU - Zuo, Jianmin

PY - 2010/3/1

Y1 - 2010/3/1

N2 - Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation

AB - Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation

KW - Immune-evasion

KW - Tumour virus

KW - Epstein-Barr virus

KW - Herpesvirus

KW - Immune response

KW - Antigen presentation

U2 - 10.1016/j.micinf.2009.12.001

DO - 10.1016/j.micinf.2009.12.001

M3 - Review article

C2 - 20004735

VL - 12

SP - 173

EP - 181

JO - Microbes and Infection

JF - Microbes and Infection

SN - 1286-4579

IS - 3

ER -