Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography

Research output: Contribution to journalArticlepeer-review

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Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography. / Brooksby, Ben; Pogue, Brian W; Jiang, Shudong; Dehghani, Hamid; Srinivasan, Subhadra; Kogel, Christine; Tosteson, Tor D; Weaver, John; Poplack, Steven P; Paulsen, Keith D.

In: National Academy of Sciences. Proceedings, Vol. 103, No. 23, 06.06.2006, p. 8828-33.

Research output: Contribution to journalArticlepeer-review

Harvard

Brooksby, B, Pogue, BW, Jiang, S, Dehghani, H, Srinivasan, S, Kogel, C, Tosteson, TD, Weaver, J, Poplack, SP & Paulsen, KD 2006, 'Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography', National Academy of Sciences. Proceedings, vol. 103, no. 23, pp. 8828-33. https://doi.org/10.1073/pnas.0509636103

APA

Brooksby, B., Pogue, B. W., Jiang, S., Dehghani, H., Srinivasan, S., Kogel, C., Tosteson, T. D., Weaver, J., Poplack, S. P., & Paulsen, K. D. (2006). Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography. National Academy of Sciences. Proceedings, 103(23), 8828-33. https://doi.org/10.1073/pnas.0509636103

Vancouver

Author

Brooksby, Ben ; Pogue, Brian W ; Jiang, Shudong ; Dehghani, Hamid ; Srinivasan, Subhadra ; Kogel, Christine ; Tosteson, Tor D ; Weaver, John ; Poplack, Steven P ; Paulsen, Keith D. / Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography. In: National Academy of Sciences. Proceedings. 2006 ; Vol. 103, No. 23. pp. 8828-33.

Bibtex

@article{9e67112b01d44268880d0abd3b3e6199,
title = "Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography",
abstract = "Magnetic resonance (MR)-guided near-infrared spectral tomography was developed and used to image adipose and fibroglandular breast tissue of 11 normal female subjects, recruited under an institutional review board-approved protocol. Images of hemoglobin, oxygen saturation, water fraction, and subcellular scattering were reconstructed and show that fibroglandular fractions of both blood and water are higher than in adipose tissue. Variation in adipose and fibroglandular tissue composition between individuals was not significantly different across the scattered and dense breast categories. Combined MR and near-infrared tomography provides fundamental molecular information about these tissue types with resolution governed by MR T1 images.",
keywords = "Adipose Tissue, Aged, Breast, Female, Hemoglobins, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Middle Aged, Spectroscopy, Near-Infrared, Tomography",
author = "Ben Brooksby and Pogue, {Brian W} and Shudong Jiang and Hamid Dehghani and Subhadra Srinivasan and Christine Kogel and Tosteson, {Tor D} and John Weaver and Poplack, {Steven P} and Paulsen, {Keith D}",
year = "2006",
month = jun,
day = "6",
doi = "10.1073/pnas.0509636103",
language = "English",
volume = "103",
pages = "8828--33",
journal = "Proceedings of the National Academy of Sciences",
issn = "1091-6490",
publisher = "National Academy of Sciences",
number = "23",

}

RIS

TY - JOUR

T1 - Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography

AU - Brooksby, Ben

AU - Pogue, Brian W

AU - Jiang, Shudong

AU - Dehghani, Hamid

AU - Srinivasan, Subhadra

AU - Kogel, Christine

AU - Tosteson, Tor D

AU - Weaver, John

AU - Poplack, Steven P

AU - Paulsen, Keith D

PY - 2006/6/6

Y1 - 2006/6/6

N2 - Magnetic resonance (MR)-guided near-infrared spectral tomography was developed and used to image adipose and fibroglandular breast tissue of 11 normal female subjects, recruited under an institutional review board-approved protocol. Images of hemoglobin, oxygen saturation, water fraction, and subcellular scattering were reconstructed and show that fibroglandular fractions of both blood and water are higher than in adipose tissue. Variation in adipose and fibroglandular tissue composition between individuals was not significantly different across the scattered and dense breast categories. Combined MR and near-infrared tomography provides fundamental molecular information about these tissue types with resolution governed by MR T1 images.

AB - Magnetic resonance (MR)-guided near-infrared spectral tomography was developed and used to image adipose and fibroglandular breast tissue of 11 normal female subjects, recruited under an institutional review board-approved protocol. Images of hemoglobin, oxygen saturation, water fraction, and subcellular scattering were reconstructed and show that fibroglandular fractions of both blood and water are higher than in adipose tissue. Variation in adipose and fibroglandular tissue composition between individuals was not significantly different across the scattered and dense breast categories. Combined MR and near-infrared tomography provides fundamental molecular information about these tissue types with resolution governed by MR T1 images.

KW - Adipose Tissue

KW - Aged

KW - Breast

KW - Female

KW - Hemoglobins

KW - Humans

KW - Image Processing, Computer-Assisted

KW - Magnetic Resonance Imaging

KW - Middle Aged

KW - Spectroscopy, Near-Infrared

KW - Tomography

U2 - 10.1073/pnas.0509636103

DO - 10.1073/pnas.0509636103

M3 - Article

C2 - 16731633

VL - 103

SP - 8828

EP - 8833

JO - Proceedings of the National Academy of Sciences

JF - Proceedings of the National Academy of Sciences

SN - 1091-6490

IS - 23

ER -