Ileo-rectal anastomosis in ulcerative colitis: results of a long-term follow-up study

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Ileo-rectal anastomosis in ulcerative colitis : results of a long-term follow-up study. / Paoluzi, O A; Di Paolo, M C; Ricci, F; Pasquali, C; Iacucci, M; Paoluzi, P.

In: The Italian Journal of Gastroenterology, Vol. 26, No. 8, 01.10.1994, p. 392-7.

Research output: Contribution to journalArticlepeer-review

Harvard

Paoluzi, OA, Di Paolo, MC, Ricci, F, Pasquali, C, Iacucci, M & Paoluzi, P 1994, 'Ileo-rectal anastomosis in ulcerative colitis: results of a long-term follow-up study', The Italian Journal of Gastroenterology, vol. 26, no. 8, pp. 392-7.

APA

Paoluzi, O. A., Di Paolo, M. C., Ricci, F., Pasquali, C., Iacucci, M., & Paoluzi, P. (1994). Ileo-rectal anastomosis in ulcerative colitis: results of a long-term follow-up study. The Italian Journal of Gastroenterology, 26(8), 392-7.

Vancouver

Author

Paoluzi, O A ; Di Paolo, M C ; Ricci, F ; Pasquali, C ; Iacucci, M ; Paoluzi, P. / Ileo-rectal anastomosis in ulcerative colitis : results of a long-term follow-up study. In: The Italian Journal of Gastroenterology. 1994 ; Vol. 26, No. 8. pp. 392-7.

Bibtex

@article{b4e42873919f4099994dfbe50f9b128a,
title = "Ileo-rectal anastomosis in ulcerative colitis: results of a long-term follow-up study",
abstract = "Colectomy with ileo-rectal anastomosis (IRA) was introduced in the 'fifties as an alternative to proctocolectomy with ileostomy in patients with ulcerative colitis (UC). Seventy-four patients affected by UC and submitted to IRA were followed up with clinical, endoscopic and histological controls for a median follow-up period of 9.5 years (range: 3-25 years). The long-term outcome was assessed by evaluating the course of the proctitis, the need for medical therapy, functional results, the need for rectal excision, and mortality during the follow-up. The patients were classified in three groups according to the type of the outcome (success: low-relapsing proctitis, rare or no need for medical therapy, good functional results; partial failure: relapsing proctitis with frequent need for medical therapy and/or poor functional results; failure: necessity of proctectomy). In order to define the prognostic value the clinical characteristics at surgery (age, gender, duration of disease, rectal inflammation, and type of surgery) were compared in the three groups. The long-term outcome was judged as a success in 46 patients (62%), partial failure in 19 patients (26%) and failure in 9 patients (12%). Only one patient developed cancer in the rectal stump (incidence: 1.3%). None of the clinical parameters at surgery except rectal inflammation influenced the outcome: patients showing moderate or severe inflammation in the rectum at surgery had a higher failure rate than those with mild or no inflammation (p < 0.02). These data confirm that colectomy with IRA is a safe surgical procedure with good functional results in most cases and with a low risk of cancer.(ABSTRACT TRUNCATED AT 250 WORDS)",
keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Anastomosis, Surgical, Child, Colectomy, Colitis, Ulcerative, Female, Follow-Up Studies, Humans, Ileum, Male, Middle Aged, Postoperative Complications, Precancerous Conditions, Proctitis, Rectal Neoplasms, Rectum, Recurrence, Reoperation, Time Factors, Treatment Outcome, Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article",
author = "Paoluzi, {O A} and {Di Paolo}, {M C} and F Ricci and C Pasquali and M Iacucci and P Paoluzi",
year = "1994",
month = oct,
day = "1",
language = "English",
volume = "26",
pages = "392--7",
journal = "The Italian Journal of Gastroenterology",
issn = "0392-0623",
number = "8",

}

RIS

TY - JOUR

T1 - Ileo-rectal anastomosis in ulcerative colitis

T2 - results of a long-term follow-up study

AU - Paoluzi, O A

AU - Di Paolo, M C

AU - Ricci, F

AU - Pasquali, C

AU - Iacucci, M

AU - Paoluzi, P

PY - 1994/10/1

Y1 - 1994/10/1

N2 - Colectomy with ileo-rectal anastomosis (IRA) was introduced in the 'fifties as an alternative to proctocolectomy with ileostomy in patients with ulcerative colitis (UC). Seventy-four patients affected by UC and submitted to IRA were followed up with clinical, endoscopic and histological controls for a median follow-up period of 9.5 years (range: 3-25 years). The long-term outcome was assessed by evaluating the course of the proctitis, the need for medical therapy, functional results, the need for rectal excision, and mortality during the follow-up. The patients were classified in three groups according to the type of the outcome (success: low-relapsing proctitis, rare or no need for medical therapy, good functional results; partial failure: relapsing proctitis with frequent need for medical therapy and/or poor functional results; failure: necessity of proctectomy). In order to define the prognostic value the clinical characteristics at surgery (age, gender, duration of disease, rectal inflammation, and type of surgery) were compared in the three groups. The long-term outcome was judged as a success in 46 patients (62%), partial failure in 19 patients (26%) and failure in 9 patients (12%). Only one patient developed cancer in the rectal stump (incidence: 1.3%). None of the clinical parameters at surgery except rectal inflammation influenced the outcome: patients showing moderate or severe inflammation in the rectum at surgery had a higher failure rate than those with mild or no inflammation (p < 0.02). These data confirm that colectomy with IRA is a safe surgical procedure with good functional results in most cases and with a low risk of cancer.(ABSTRACT TRUNCATED AT 250 WORDS)

AB - Colectomy with ileo-rectal anastomosis (IRA) was introduced in the 'fifties as an alternative to proctocolectomy with ileostomy in patients with ulcerative colitis (UC). Seventy-four patients affected by UC and submitted to IRA were followed up with clinical, endoscopic and histological controls for a median follow-up period of 9.5 years (range: 3-25 years). The long-term outcome was assessed by evaluating the course of the proctitis, the need for medical therapy, functional results, the need for rectal excision, and mortality during the follow-up. The patients were classified in three groups according to the type of the outcome (success: low-relapsing proctitis, rare or no need for medical therapy, good functional results; partial failure: relapsing proctitis with frequent need for medical therapy and/or poor functional results; failure: necessity of proctectomy). In order to define the prognostic value the clinical characteristics at surgery (age, gender, duration of disease, rectal inflammation, and type of surgery) were compared in the three groups. The long-term outcome was judged as a success in 46 patients (62%), partial failure in 19 patients (26%) and failure in 9 patients (12%). Only one patient developed cancer in the rectal stump (incidence: 1.3%). None of the clinical parameters at surgery except rectal inflammation influenced the outcome: patients showing moderate or severe inflammation in the rectum at surgery had a higher failure rate than those with mild or no inflammation (p < 0.02). These data confirm that colectomy with IRA is a safe surgical procedure with good functional results in most cases and with a low risk of cancer.(ABSTRACT TRUNCATED AT 250 WORDS)

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Anastomosis, Surgical

KW - Child

KW - Colectomy

KW - Colitis, Ulcerative

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Ileum

KW - Male

KW - Middle Aged

KW - Postoperative Complications

KW - Precancerous Conditions

KW - Proctitis

KW - Rectal Neoplasms

KW - Rectum

KW - Recurrence

KW - Reoperation

KW - Time Factors

KW - Treatment Outcome

KW - Clinical Trial

KW - Comparative Study

KW - Controlled Clinical Trial

KW - Journal Article

M3 - Article

C2 - 7703514

VL - 26

SP - 392

EP - 397

JO - The Italian Journal of Gastroenterology

JF - The Italian Journal of Gastroenterology

SN - 0392-0623

IS - 8

ER -