Identification of Amino Acid Residues within the N-Terminal Domain of EspA That Play a Role in EspA Filament Biogenesis and Function

MP Singh, Robert Shaw, Stuart Knutton, Mark Pallen, VF Crepin, G Frankel

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Enteropathogenic Escherichia coli employs a filamentous type III secretion system, made by homopolymerization of the translocator protein EspA. In this study, we have shown that the N-terminal region of EspA has a role in EspA's protein stability, interaction with the CesAB chaperone, and filament biogenesis and function.
Original languageEnglish
Pages (from-to)2221-2226
Number of pages6
JournalJournal of Bacteriology
Volume190
Issue number6
Early online date4 Jan 2008
DOIs
Publication statusPublished - 4 Jan 2008

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