Ideational action impairments in Alzheimer’s disease

Research output: Contribution to journalArticle

Authors

Colleges, School and Institutes

Abstract

We report data from a group of patients with mild Alzheimer's disease on a range of tasks requiring either stored semantic knowledge about objects (e.g., naming object use) or the execution of action to objects (e.g., miming and using objects). We found that the patients were impaired at miming in response to objects, even when they could describe the object's function. On the other hand, copying gestures was not impaired relative to naming gestures, indicating that an ideomotor deficit in action execution, per se, was unlikely to explain the impairments in object use. We suggest instead that the patients had an impairment in stored motor programmes for action, over and above their deficits in semantic knowledge. Despite this, the patients were better at using than at miming to objects, consistent with the view that proprioceptive input (when using objects) can directly constrain selection of the appropriate motor programme for action.

Details

Original languageEnglish
Pages (from-to)198-205
Number of pages8
JournalBrain and Cognition
Volume62
Issue number3
Publication statusPublished - 1 Dec 2006

Keywords

  • semantic memory, action knowledge, ideomotor apraxia, ideational apraxia, Alzheimer's disease, action production