Hysteroscopic local anesthetic intrauterine cornual block in office endometrial ablation: a randomized controlled trial

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@article{6aff40460d604c768fd7b7964a9b784c,
title = "Hysteroscopic local anesthetic intrauterine cornual block in office endometrial ablation: a randomized controlled trial",
abstract = "OBJECTIVE: To evaluate the efficacy of a hysteroscopic local anesthetic intrauterine cornual block (ICOB) on pain experienced during office endometrial ablation (EA) in addition to a traditional direct local anesthetic cervical block (DCB).DESIGN: Prospective, randomized, double-blind, placebo-controlled trial.SETTING: University teaching hospital.PATIENT(S): Women with heavy menstrual bleeding scheduled for an office endometrial ablation.INTERVENTION(S): Before office EA, DCB plus hysteroscopic ICOB just medial to each tubal ostium using local anesthetic mixture made up of 1 mL 3% mepivacaine plus 1 mL 0.5% bupivacaine versus control group receiving DBC plus ICOB with 2 mL of placebo (saline).MAIN OUTCOME MEASURE(S): Primary outcome: pain reported during procedure via visual analogue scale (VAS) from 0 to 10; secondary outcomes: postoperative pain, rescue analgesic requirement, and duration of hospital stay.RESULT(S): Most characteristics were similar across groups. The mean VAS score during the procedure was statistically significantly lower by 1.44 (95% confidence interval, -2.65 to -0.21) in the active group compared with the placebo group. There were no statistically significant differences between the two groups in the postprocedural mean VAS scores, rescue analgesic requirement, or duration of hospital stay.CONCLUSION(S): Used in addition to DCB, ICOB reduces the pain experienced during office EA compared with DCB alone.CLINICAL TRIAL REGISTRATION NUMBER: NCT01808898.",
author = "Vinod Kumar and Konstantinos Tryposkiadis and Gupta, {Janesh Kumar}",
note = "Copyright {\textcopyright} 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.",
year = "2015",
month = nov,
day = "4",
doi = "10.1016/j.fertnstert.2015.10.019",
language = "English",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Hysteroscopic local anesthetic intrauterine cornual block in office endometrial ablation

T2 - a randomized controlled trial

AU - Kumar, Vinod

AU - Tryposkiadis, Konstantinos

AU - Gupta, Janesh Kumar

N1 - Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

PY - 2015/11/4

Y1 - 2015/11/4

N2 - OBJECTIVE: To evaluate the efficacy of a hysteroscopic local anesthetic intrauterine cornual block (ICOB) on pain experienced during office endometrial ablation (EA) in addition to a traditional direct local anesthetic cervical block (DCB).DESIGN: Prospective, randomized, double-blind, placebo-controlled trial.SETTING: University teaching hospital.PATIENT(S): Women with heavy menstrual bleeding scheduled for an office endometrial ablation.INTERVENTION(S): Before office EA, DCB plus hysteroscopic ICOB just medial to each tubal ostium using local anesthetic mixture made up of 1 mL 3% mepivacaine plus 1 mL 0.5% bupivacaine versus control group receiving DBC plus ICOB with 2 mL of placebo (saline).MAIN OUTCOME MEASURE(S): Primary outcome: pain reported during procedure via visual analogue scale (VAS) from 0 to 10; secondary outcomes: postoperative pain, rescue analgesic requirement, and duration of hospital stay.RESULT(S): Most characteristics were similar across groups. The mean VAS score during the procedure was statistically significantly lower by 1.44 (95% confidence interval, -2.65 to -0.21) in the active group compared with the placebo group. There were no statistically significant differences between the two groups in the postprocedural mean VAS scores, rescue analgesic requirement, or duration of hospital stay.CONCLUSION(S): Used in addition to DCB, ICOB reduces the pain experienced during office EA compared with DCB alone.CLINICAL TRIAL REGISTRATION NUMBER: NCT01808898.

AB - OBJECTIVE: To evaluate the efficacy of a hysteroscopic local anesthetic intrauterine cornual block (ICOB) on pain experienced during office endometrial ablation (EA) in addition to a traditional direct local anesthetic cervical block (DCB).DESIGN: Prospective, randomized, double-blind, placebo-controlled trial.SETTING: University teaching hospital.PATIENT(S): Women with heavy menstrual bleeding scheduled for an office endometrial ablation.INTERVENTION(S): Before office EA, DCB plus hysteroscopic ICOB just medial to each tubal ostium using local anesthetic mixture made up of 1 mL 3% mepivacaine plus 1 mL 0.5% bupivacaine versus control group receiving DBC plus ICOB with 2 mL of placebo (saline).MAIN OUTCOME MEASURE(S): Primary outcome: pain reported during procedure via visual analogue scale (VAS) from 0 to 10; secondary outcomes: postoperative pain, rescue analgesic requirement, and duration of hospital stay.RESULT(S): Most characteristics were similar across groups. The mean VAS score during the procedure was statistically significantly lower by 1.44 (95% confidence interval, -2.65 to -0.21) in the active group compared with the placebo group. There were no statistically significant differences between the two groups in the postprocedural mean VAS scores, rescue analgesic requirement, or duration of hospital stay.CONCLUSION(S): Used in addition to DCB, ICOB reduces the pain experienced during office EA compared with DCB alone.CLINICAL TRIAL REGISTRATION NUMBER: NCT01808898.

U2 - 10.1016/j.fertnstert.2015.10.019

DO - 10.1016/j.fertnstert.2015.10.019

M3 - Article

C2 - 26546298

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

ER -