Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium

C Feldman; R Cockeran; M J Jedrzejas; T J Mitchell; R Anderson

doi:10.1016/j.ijid.2005.09.002

Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium

C Feldman, R Cockeran, M J Jedrzejas, T J Mitchell, R Anderson

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

The main objective of this study was to investigate the effects of pneumococcal hyaluronidase (0.1-10microg/ml), alone and in combination with pneumolysin (50 and 100ng/ml), on human ciliated epithelium.

Original language	English
Pages (from-to)	11-5
Number of pages	5
Journal	International Journal of Infectious Diseases
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/j.ijid.2005.09.002
Publication status	Published - Jan 2007

Keywords

Bacterial Proteins
Calcium
Cilia
Dose-Response Relationship, Drug
Drug Synergism
Epithelium
Erythrocytes
Humans
Hyaluronoglucosaminidase
Neutrophils
Streptolysins

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10.1016/j.ijid.2005.09.002

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title = "Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium",

abstract = "The main objective of this study was to investigate the effects of pneumococcal hyaluronidase (0.1-10microg/ml), alone and in combination with pneumolysin (50 and 100ng/ml), on human ciliated epithelium.",

keywords = "Bacterial Proteins, Calcium, Cilia, Dose-Response Relationship, Drug, Drug Synergism, Epithelium, Erythrocytes, Humans, Hyaluronoglucosaminidase, Neutrophils, Streptolysins",

author = "C Feldman and R Cockeran and Jedrzejas, {M J} and Mitchell, {T J} and R Anderson",

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AU - Cockeran, R

AU - Jedrzejas, M J

AU - Mitchell, T J

AU - Anderson, R

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KW - Bacterial Proteins

KW - Calcium

KW - Cilia

KW - Dose-Response Relationship, Drug

KW - Drug Synergism

KW - Epithelium

KW - Erythrocytes

KW - Humans

KW - Hyaluronoglucosaminidase

KW - Neutrophils

KW - Streptolysins

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DO - 10.1016/j.ijid.2005.09.002

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SN - 1201-9712

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EP - 15

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

IS - 1

ER -

Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium

Abstract

Keywords

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