Huntington's disease

S Davies, David Ramsden

Research output: Contribution to journalReview articlepeer-review

81 Citations (Scopus)

Abstract

The most recent findings in the elucidation of the molecular pathology of Huntington's disease are reviewed. Particular interest has been paid to the role of huntingtin and its associated proteins in excitotoxicity mediated via NMDA and kainate receptors.
Original languageEnglish
Pages (from-to)409-413
Number of pages5
JournalMolecular Pathology
Volume54
Issue number6
DOIs
Publication statusPublished - 1 Dec 2001

Keywords

  • Huntington's disease
  • Huntingtin
  • neurodegenerative disorder
  • NMDA receptors
  • kainate receptors

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