Human papillomavirus infection and risk of progression of epithelial abnormalities of the cervix

Research output: Contribution to journalArticle

Authors

  • Ciaran Woodman
  • Terence Rollason
  • J Ellis
  • S Wilson

Abstract

The polymerase chain reaction has been used to determine the presence of human papillomavirus (HPV) 16 and HPV 18 DNA sequences in archival histological material removed from a cohort of untreated women with cervical epithelial abnormalities. The detection of HPV 16 or HPV 18 DNA sequences in the initial biopsy specimen was associated with a significantly increased risk of subsequent disease progression.

Details

Original languageEnglish
Pages (from-to)553-556
Number of pages4
JournalBritish Journal of Cancer
Volume73
Issue number4
Publication statusPublished - Feb 1996

Keywords

  • Cervical Intraepithelial Neoplasia, Cervix Uteri, Cohort Studies, DNA, Viral, Disease Progression, Female, Follow-Up Studies, Humans, Papillomaviridae, Papillomavirus Infections, Polymerase Chain Reaction, Risk Factors, Time Factors, Tumor Virus Infections

ASJC Scopus subject areas