Human consciousness is supported by dynamic complex patterns of brain signal coordination: distinct brain patterns sustain conscious states

Research output: Contribution to journal › Article

Standard

Human consciousness is supported by dynamic complex patterns of brain signal coordination : distinct brain patterns sustain conscious states. / Demertzi, Athena; Tagliazucchi, Enzo; Dehaene, Stanislas; Deco, Gustavo; Barttfeld, Pablo; Raimondo, Federico; Martial, Charlotte; Fernandez-Espejo, Davinia; Rohaut, Benjamin; Voss, Henning; Schiff, Nicholas; Owen, Adrian; Laureys, Steven; Naccache, Lionel; Sitt, Jacobo.

In: Science Advances, Vol. 5, No. 2, eaat7603, 06.02.2019, p. eaat7603.

Research output: Contribution to journal › Article

Harvard

Demertzi, A, Tagliazucchi, E, Dehaene, S, Deco, G, Barttfeld, P, Raimondo, F, Martial, C, Fernandez-Espejo, D, Rohaut, B, Voss, H, Schiff, N, Owen, A, Laureys, S, Naccache, L & Sitt, J 2019, 'Human consciousness is supported by dynamic complex patterns of brain signal coordination: distinct brain patterns sustain conscious states', Science Advances, vol. 5, no. 2, eaat7603, pp. eaat7603. https://doi.org/10.1126/sciadv.aat7603

APA

Demertzi, A., Tagliazucchi, E., Dehaene, S., Deco, G., Barttfeld, P., Raimondo, F., ... Sitt, J. (2019). Human consciousness is supported by dynamic complex patterns of brain signal coordination: distinct brain patterns sustain conscious states. Science Advances, 5(2), eaat7603. [eaat7603]. https://doi.org/10.1126/sciadv.aat7603

Vancouver

Demertzi A, Tagliazucchi E, Dehaene S, Deco G, Barttfeld P, Raimondo F et al. Human consciousness is supported by dynamic complex patterns of brain signal coordination: distinct brain patterns sustain conscious states. Science Advances. 2019 Feb 6;5(2):eaat7603. eaat7603. https://doi.org/10.1126/sciadv.aat7603

Author

Demertzi, Athena ; Tagliazucchi, Enzo ; Dehaene, Stanislas ; Deco, Gustavo ; Barttfeld, Pablo ; Raimondo, Federico ; Martial, Charlotte ; Fernandez-Espejo, Davinia ; Rohaut, Benjamin ; Voss, Henning ; Schiff, Nicholas ; Owen, Adrian ; Laureys, Steven ; Naccache, Lionel ; Sitt, Jacobo. / Human consciousness is supported by dynamic complex patterns of brain signal coordination : distinct brain patterns sustain conscious states. In: Science Advances. 2019 ; Vol. 5, No. 2. pp. eaat7603.

Bibtex

@article{14d071c2d67c4e48b00193df1a42fd0a,
title = "Human consciousness is supported by dynamic complex patterns of brain signal coordination: distinct brain patterns sustain conscious states",
abstract = "Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. The complex pattern was further corroborated in patients with covert cognition, who could perform neuroimaging mental imagery tasks, validating this pattern’s implication in consciousness. Anesthesia increased the probability of the less complex pattern to equal levels, validating its implication in unconsciousness. Our results establish that consciousness rests on the brain’s ability to sustain rich brain dynamics and pave the way for determining specific and generalizable fingerprints of conscious and unconscious states.",
author = "Athena Demertzi and Enzo Tagliazucchi and Stanislas Dehaene and Gustavo Deco and Pablo Barttfeld and Federico Raimondo and Charlotte Martial and Davinia Fernandez-Espejo and Benjamin Rohaut and Henning Voss and Nicholas Schiff and Adrian Owen and Steven Laureys and Lionel Naccache and Jacobo Sitt",
year = "2019",
month = "2",
day = "6",
doi = "10.1126/sciadv.aat7603",
language = "English",
volume = "5",
pages = "eaat7603",
journal = "Science Advances",
issn = "2375-2548",
publisher = "American Association for the Advancement of Science",
number = "2",

}

RIS

TY - JOUR

T1 - Human consciousness is supported by dynamic complex patterns of brain signal coordination

T2 - distinct brain patterns sustain conscious states

AU - Demertzi, Athena

AU - Tagliazucchi, Enzo

AU - Dehaene, Stanislas

AU - Deco, Gustavo

AU - Barttfeld, Pablo

AU - Raimondo, Federico

AU - Martial, Charlotte

AU - Fernandez-Espejo, Davinia

AU - Rohaut, Benjamin

AU - Voss, Henning

AU - Schiff, Nicholas

AU - Owen, Adrian

AU - Laureys, Steven

AU - Naccache, Lionel

AU - Sitt, Jacobo

PY - 2019/2/6

Y1 - 2019/2/6

N2 - Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. The complex pattern was further corroborated in patients with covert cognition, who could perform neuroimaging mental imagery tasks, validating this pattern’s implication in consciousness. Anesthesia increased the probability of the less complex pattern to equal levels, validating its implication in unconsciousness. Our results establish that consciousness rests on the brain’s ability to sustain rich brain dynamics and pave the way for determining specific and generalizable fingerprints of conscious and unconscious states.

AB - Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. The complex pattern was further corroborated in patients with covert cognition, who could perform neuroimaging mental imagery tasks, validating this pattern’s implication in consciousness. Anesthesia increased the probability of the less complex pattern to equal levels, validating its implication in unconsciousness. Our results establish that consciousness rests on the brain’s ability to sustain rich brain dynamics and pave the way for determining specific and generalizable fingerprints of conscious and unconscious states.

U2 - 10.1126/sciadv.aat7603

DO - 10.1126/sciadv.aat7603

M3 - Article

VL - 5

SP - eaat7603

JO - Science Advances

JF - Science Advances

SN - 2375-2548

IS - 2

M1 - eaat7603

ER -