Highly regioselective synthesis of 2,4,5-(hetero)aryl substituted oxazoles by intermolecular [3+2]-cycloaddition of unsymmetrical internal alkynes

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A robust N-nucleophilic 1,3-N,O-dipole equivalent reacts with unsymmetrical internal alkynes under gold catalysis. Conjugation from a remote nitrogen lone pair enables and controls this convergent and highly regioselective process. This journal is © 2013 The Royal Society of Chemistry.


Original languageEnglish
Pages (from-to)8617-8619
Number of pages3
JournalChemical Communications
Issue number77
Publication statusPublished - 7 Oct 2013

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