High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells

Research output: Contribution to journalArticle

Colleges, School and Institutes

Abstract

Gold nanoparticles are efficiently labelled with a luminescent ruthenium complex, producing 13 and 100 nm diameter, monodisperse red-emissive imaging probes with luminescence lifetimes prolonged over the molecular unit. Single, 100 nm particles are observed in whole cell luminescence imaging which reveals their biomolecular association with chromatin in the nucleus of cancer cells.

Details

Original languageEnglish
Pages (from-to)617-9
Number of pages3
JournalChemical Communications
Volume50
Issue number5
Early online date5 Nov 2013
Publication statusPublished - 18 Jan 2014

Keywords

  • Cell Line, Tumor, Coordination Complexes, Gold, Humans, Metal Nanoparticles, Microscopy, Confocal, Particle Size, Ruthenium