Heart Failure and Stroke

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Heart Failure and Stroke. / Schumacher, Katja; Kornej, Jelena; Shantsila, Eduard; Lip, Gregory Y H.

In: Current heart failure reports, 30.07.2018.

Research output: Contribution to journalReview article

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@article{3afa0941379849d5bc5cac0ce3926119,
title = "Heart Failure and Stroke",
abstract = "PURPOSE: Ischemic stroke significantly contributes to morbidity and mortality in heart failure (HF). The risk of stroke increases significantly, with coexisting atrial fibrillation (AF). An aggravating factor could be asymptomatic paroxysms of AF (so-called silent AF), and therefore, the risk stratification in these patients remains difficult. This review provides an overview of stroke risk in HF, its risk stratification, and stroke prevention in these patients.RECENT FINDINGS: Stroke risk stratification in HF patients remains an important issue. Recently, the CHA2DS2-VASc score, originally developed to predict stroke risk in AF patients, had been reported to be a predictive for strokes in HF patients regardless of AF being present. Furthermore, there are several independent risk factors (e.g., hypertension, diabetes mellitus, prior stroke) described. Based on the current evidence, HF should be considered as an independent risk factor for stroke. The CHA2DS2-VASc score might be useful to predict stroke risk in HF patients with or without AF in clinical routine. However, there is only a recommendation for the oral anticoagulation use in patients with concomitant HF and AF, while in patients with HF and no AF, individualized risk stratification is preferred. Current guidelines recommend to prefer non-vitamin Kantagonist anticoagulants over warfarin.",
keywords = "Heart failure, Risk stratification, Silent atrial fibrillation, Stroke, Stroke prevention",
author = "Katja Schumacher and Jelena Kornej and Eduard Shantsila and Lip, {Gregory Y H}",
year = "2018",
month = jul,
day = "30",
doi = "10.1007/s11897-018-0405-9",
language = "English",
journal = "Current heart failure reports",
issn = "1546-9530",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Heart Failure and Stroke

AU - Schumacher, Katja

AU - Kornej, Jelena

AU - Shantsila, Eduard

AU - Lip, Gregory Y H

PY - 2018/7/30

Y1 - 2018/7/30

N2 - PURPOSE: Ischemic stroke significantly contributes to morbidity and mortality in heart failure (HF). The risk of stroke increases significantly, with coexisting atrial fibrillation (AF). An aggravating factor could be asymptomatic paroxysms of AF (so-called silent AF), and therefore, the risk stratification in these patients remains difficult. This review provides an overview of stroke risk in HF, its risk stratification, and stroke prevention in these patients.RECENT FINDINGS: Stroke risk stratification in HF patients remains an important issue. Recently, the CHA2DS2-VASc score, originally developed to predict stroke risk in AF patients, had been reported to be a predictive for strokes in HF patients regardless of AF being present. Furthermore, there are several independent risk factors (e.g., hypertension, diabetes mellitus, prior stroke) described. Based on the current evidence, HF should be considered as an independent risk factor for stroke. The CHA2DS2-VASc score might be useful to predict stroke risk in HF patients with or without AF in clinical routine. However, there is only a recommendation for the oral anticoagulation use in patients with concomitant HF and AF, while in patients with HF and no AF, individualized risk stratification is preferred. Current guidelines recommend to prefer non-vitamin Kantagonist anticoagulants over warfarin.

AB - PURPOSE: Ischemic stroke significantly contributes to morbidity and mortality in heart failure (HF). The risk of stroke increases significantly, with coexisting atrial fibrillation (AF). An aggravating factor could be asymptomatic paroxysms of AF (so-called silent AF), and therefore, the risk stratification in these patients remains difficult. This review provides an overview of stroke risk in HF, its risk stratification, and stroke prevention in these patients.RECENT FINDINGS: Stroke risk stratification in HF patients remains an important issue. Recently, the CHA2DS2-VASc score, originally developed to predict stroke risk in AF patients, had been reported to be a predictive for strokes in HF patients regardless of AF being present. Furthermore, there are several independent risk factors (e.g., hypertension, diabetes mellitus, prior stroke) described. Based on the current evidence, HF should be considered as an independent risk factor for stroke. The CHA2DS2-VASc score might be useful to predict stroke risk in HF patients with or without AF in clinical routine. However, there is only a recommendation for the oral anticoagulation use in patients with concomitant HF and AF, while in patients with HF and no AF, individualized risk stratification is preferred. Current guidelines recommend to prefer non-vitamin Kantagonist anticoagulants over warfarin.

KW - Heart failure

KW - Risk stratification

KW - Silent atrial fibrillation

KW - Stroke

KW - Stroke prevention

U2 - 10.1007/s11897-018-0405-9

DO - 10.1007/s11897-018-0405-9

M3 - Review article

C2 - 30062623

JO - Current heart failure reports

JF - Current heart failure reports

SN - 1546-9530

ER -