Growth of Clostridium difficile and production of toxins A and B in complex and defined media

S C Haslam, J M Ketley, T J Mitchell, J Stephen, D W Burdon, D C Candy

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51 Citations (Scopus)

Abstract

The ability of several strains of Clostridium difficile to grow and to produce toxins A and B in complex and defined culture media has been studied with special reference to the amino-acid composition of the medium. The production of these toxins varied with the strain used and with the composition of the growth medium. Toxin A production was not inextricably linked to production of toxin B since conditions were found in which only one or other toxin was produced.

Original languageEnglish
Pages (from-to)293-7
Number of pages5
JournalJournal of Medical Microbiology
Volume21
Issue number4
DOIs
Publication statusPublished - Jun 1986

Keywords

  • Amino Acids
  • Bacterial Proteins
  • Bacterial Toxins
  • Clostridium
  • Culture Media
  • Enterotoxins

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