Growth of Clostridium difficile and production of toxins A and B in complex and defined media

Research output: Contribution to journalArticlepeer-review


Colleges, School and Institutes


The ability of several strains of Clostridium difficile to grow and to produce toxins A and B in complex and defined culture media has been studied with special reference to the amino-acid composition of the medium. The production of these toxins varied with the strain used and with the composition of the growth medium. Toxin A production was not inextricably linked to production of toxin B since conditions were found in which only one or other toxin was produced.


Original languageEnglish
Pages (from-to)293-7
Number of pages5
JournalJournal of Medical Microbiology
Issue number4
Publication statusPublished - Jun 1986


  • Amino Acids, Bacterial Proteins, Bacterial Toxins, Clostridium, Culture Media, Enterotoxins