GREVE: Genomic Recurrent Event ViEwer to assist the identification of patterns across individual cancer samples

Research output: Contribution to journalArticlepeer-review

Authors

Colleges, School and Institutes

Abstract

SUMMARY: GREVE has been developed to assist with the identification of recurrent genomic aberrations across cancer samples. The exact characterization of such aberrations remains a challenge despite the availability of increasing amount of data, from SNParray to next-generation sequencing. Furthermore, genomic aberrations in cancer are especially difficult to handle because they are, by nature, unique to the patients. However, their recurrence in specific regions of the genome has been shown to reflect their relevance in the development of tumors. GREVE makes use of previously characterized events to identify such regions and focus any further analysis.

AVAILABILITY: GREVE is available through a web interface and open-source application (http://www.well.ox.ac.uk/GREVE).

Details

Original languageEnglish
Pages (from-to)2981-2
Number of pages2
JournalBioinformatics
Volume28
Issue number22
Publication statusPublished - 15 Nov 2012

Keywords

  • Chromosome Aberrations, Chromosome Breakpoints, Genome, Human, Humans, Neoplasms, Software