Glucose-sensitive hydrogel optical fibers functionalized with phenylboronic acid

Ali K Yetisen; Nan Jiang; Afsoon Fallahi; Yunuen Montelongo; Guillermo U Ruiz-Esparza; Ali Tamayol; Yu Shrike Zhang; Iram Mahmood; Su-A Yang; Ki Su Kim; Haider Butt; Ali Khademhosseini; Seok-Hyun Yun

doi:10.1002/adma.201606380

Glucose-sensitive hydrogel optical fibers functionalized with phenylboronic acid

Ali K Yetisen, Nan Jiang, Afsoon Fallahi, Yunuen Montelongo, Guillermo U Ruiz-Esparza, Ali Tamayol, Yu Shrike Zhang, Iram Mahmood, Su-A Yang, Ki Su Kim, Haider Butt, Ali Khademhosseini, Seok-Hyun Yun

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Abstract

Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide-co-poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis-diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.

Original language	English
Article number	1606380
Journal	Advanced Materials
Volume	29
Issue number	15
Early online date	13 Feb 2017
DOIs	https://doi.org/10.1002/adma.201606380
Publication status	Published - 18 Apr 2017

Keywords

diagnostics
fiber optics
glucose sensing
hydrogels
light transmission

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Yetisen_et_al_Glucose-Sensitive_Hydrogel_Optical_Fibers_Adavanced_MaterialsFinal published version, 3.24 MBLicence: Creative Commons: Attribution (CC BY)

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Yetisen, A. K., Jiang, N., Fallahi, A., Montelongo, Y., Ruiz-Esparza, G. U., Tamayol, A., Zhang, Y. S., Mahmood, I., Yang, S-A., Kim, K. S., Butt, H., Khademhosseini, A., & Yun, S-H. (2017). Glucose-sensitive hydrogel optical fibers functionalized with phenylboronic acid. Advanced Materials, 29(15), Article 1606380. Advance online publication. https://doi.org/10.1002/adma.201606380

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abstract = "Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide-co-poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis-diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.",

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note = "{\textcopyright} 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",

year = "2017",

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AU - Yetisen, Ali K

AU - Jiang, Nan

AU - Fallahi, Afsoon

AU - Montelongo, Yunuen

AU - Ruiz-Esparza, Guillermo U

AU - Tamayol, Ali

AU - Zhang, Yu Shrike

AU - Mahmood, Iram

AU - Yang, Su-A

AU - Kim, Ki Su

AU - Butt, Haider

AU - Khademhosseini, Ali

AU - Yun, Seok-Hyun

PY - 2017/4/18

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AB - Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide-co-poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis-diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.

KW - diagnostics

KW - fiber optics

KW - glucose sensing

KW - hydrogels

KW - light transmission

U2 - 10.1002/adma.201606380

DO - 10.1002/adma.201606380

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JO - Advanced Materials

JF - Advanced Materials

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M1 - 1606380

ER -

Glucose-sensitive hydrogel optical fibers functionalized with phenylboronic acid

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