Glucose selective surface plasmon resonance-based bis-boronic acid sensor

Alexander Stephenson-Brown; Hui-chen Wang; Parvez Iqbal; Jon A. Preece; Yitao Long; John S. Fossey; Tony D. James; Paula M. Mendes

doi:10.1039/c3an01233f

Glucose selective surface plasmon resonance-based bis-boronic acid sensor

Alexander Stephenson-Brown, Hui-chen Wang, Parvez Iqbal, Jon A. Preece, Yitao Long, John S. Fossey, Tony D. James, Paula M. Mendes

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

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Abstract

Saccharides – a versatile class of biologically important molecules – are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect D-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely D-galactose, D-fructose and D-mannose.

Original language	English
Pages (from-to)	7140-7145
Number of pages	6
Journal	The Analyst
Volume	138
Issue number	23
DOIs	https://doi.org/10.1039/c3an01233f
Publication status	Published - 7 Dec 2013

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10.1039/c3an01233f

Fossey_Glucose_selective_surface_Analyst_2013
Eligibility for repository : checked 02/04/2014
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Boronic Acids for Dye Sensitised Solar Cells
Fossey, J.
Engineering & Physical Science Research Council
23/04/12 → 22/04/14
Project: Research

Cite this

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AU - Stephenson-Brown, Alexander

AU - Wang, Hui-chen

AU - Iqbal, Parvez

AU - Preece, Jon A.

AU - Long, Yitao

AU - Fossey, John S.

AU - James, Tony D.

AU - Mendes, Paula M.

PY - 2013/12/7

Y1 - 2013/12/7

N2 - Saccharides – a versatile class of biologically important molecules – are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect D-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely D-galactose, D-fructose and D-mannose.

AB - Saccharides – a versatile class of biologically important molecules – are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect D-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely D-galactose, D-fructose and D-mannose.

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DO - 10.1039/c3an01233f

M3 - Article

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VL - 138

SP - 7140

EP - 7145

JO - The Analyst

JF - The Analyst

IS - 23

ER -

Glucose selective surface plasmon resonance-based bis-boronic acid sensor

Abstract

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Projects

Boronic Acids for Dye Sensitised Solar Cells

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