Glucose selective surface plasmon resonance-based bis-boronic acid sensor

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Colleges, School and Institutes


Saccharides – a versatile class of biologically important molecules – are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect D-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely D-galactose, D-fructose and D-mannose.


Original languageEnglish
Pages (from-to)7140-7145
Number of pages6
JournalThe Analyst
Issue number23
Publication statusPublished - 7 Dec 2013