Genetics in ocular inflammation--basic principles.

Research output: Contribution to journalArticle

Colleges, School and Institutes

Abstract

The ability to identify individuals at risk of ocular disease, or to determine the potential severity of disease or response to therapy is the current focus of much research. These studies are being led by genetic analysis of individuals to determine associations with alterations in gens that may explain manifestations of particular diseases. In this review we consider the basic principles behind genetic studies in general and of ocular disease in particular. We address the methodologies being utilised, and the results derived so far. The potential and pitfalls of such studies are relevant to the concept of personalised medicine and better defined clinical trials.

Details

Original languageEnglish
Pages (from-to)10-8
Number of pages9
JournalOcular immunology and inflammation
Volume19
Issue number1
Publication statusPublished - 1 Feb 2011