Generalized anxiety and major depressive disorders, their comorbidity and hypertension in middle-aged men.

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Generalized anxiety and major depressive disorders, their comorbidity and hypertension in middle-aged men. / Carroll, Douglas; Phillips, Anna; Gale, CR; Batty, GD.

In: Psychosomatic Medicine, Vol. 72, No. 1, 01.01.2010, p. 16-9.

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@article{30f6223d58a94c23b435bc90cb96fa09,
title = "Generalized anxiety and major depressive disorders, their comorbidity and hypertension in middle-aged men.",
abstract = "OBJECTIVE: To examine the cross-sectional associations between generalized anxiety disorder (GAD) and major depressive disorder (MDD), their comorbidity, and hypertension. METHODS: Participants (n = 4180) were drawn from a cohort of men who were members of the U.S. army during the Vietnam war era. Occupational, sociodemographic, and health data were collected from military service files, telephone interviews, and medical examinations. Hypertension status was defined by the presence of one of the following: self-reports at interview of either a physician-diagnosis or taking antihypertensive medication; or an average systolic blood pressure > or = 140 mm Hg or an average diastolic blood pressure > or = 90 mm Hg at the medical examination. One-year prevalence of GAD and MDD was determined, using Diagnostic and Statistical Manual of Mental Disorders, Third Edition criteria. RESULTS: In separate regression models adjusting for age and then additionally for place of service, ethnicity, marital status, alcohol consumption, smoking, body mass index, household income, and education grade, both GAD and MDD were related positively to hypertension. In age-adjusted and fully adjusted models comparing comorbid GAD/MDD, GAD alone, MDD alone, and neither condition, comorbidity showed the strongest relationship with hypertension. CONCLUSION: Depression has been the main focus for research on mental health and physical health outcomes. The present results suggest that future research should pay equal attention to GAD and, in particular, the comorbidity of GAD and MDD.",
keywords = "major depression, fasting glucose, comorbidity, veterans, hypertension, diagnosis, Depressive symptoms, generalized anxiety disorder, major depressive disorder, type 2 diabetes",
author = "Douglas Carroll and Anna Phillips and CR Gale and GD Batty",
year = "2010",
month = jan,
day = "1",
doi = "10.1097/PSY.0b013e3181c4fca1",
language = "English",
volume = "72",
pages = "16--9",
journal = "Psychosomatic Medicine",
issn = "0033-3174",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

RIS

TY - JOUR

T1 - Generalized anxiety and major depressive disorders, their comorbidity and hypertension in middle-aged men.

AU - Carroll, Douglas

AU - Phillips, Anna

AU - Gale, CR

AU - Batty, GD

PY - 2010/1/1

Y1 - 2010/1/1

N2 - OBJECTIVE: To examine the cross-sectional associations between generalized anxiety disorder (GAD) and major depressive disorder (MDD), their comorbidity, and hypertension. METHODS: Participants (n = 4180) were drawn from a cohort of men who were members of the U.S. army during the Vietnam war era. Occupational, sociodemographic, and health data were collected from military service files, telephone interviews, and medical examinations. Hypertension status was defined by the presence of one of the following: self-reports at interview of either a physician-diagnosis or taking antihypertensive medication; or an average systolic blood pressure > or = 140 mm Hg or an average diastolic blood pressure > or = 90 mm Hg at the medical examination. One-year prevalence of GAD and MDD was determined, using Diagnostic and Statistical Manual of Mental Disorders, Third Edition criteria. RESULTS: In separate regression models adjusting for age and then additionally for place of service, ethnicity, marital status, alcohol consumption, smoking, body mass index, household income, and education grade, both GAD and MDD were related positively to hypertension. In age-adjusted and fully adjusted models comparing comorbid GAD/MDD, GAD alone, MDD alone, and neither condition, comorbidity showed the strongest relationship with hypertension. CONCLUSION: Depression has been the main focus for research on mental health and physical health outcomes. The present results suggest that future research should pay equal attention to GAD and, in particular, the comorbidity of GAD and MDD.

AB - OBJECTIVE: To examine the cross-sectional associations between generalized anxiety disorder (GAD) and major depressive disorder (MDD), their comorbidity, and hypertension. METHODS: Participants (n = 4180) were drawn from a cohort of men who were members of the U.S. army during the Vietnam war era. Occupational, sociodemographic, and health data were collected from military service files, telephone interviews, and medical examinations. Hypertension status was defined by the presence of one of the following: self-reports at interview of either a physician-diagnosis or taking antihypertensive medication; or an average systolic blood pressure > or = 140 mm Hg or an average diastolic blood pressure > or = 90 mm Hg at the medical examination. One-year prevalence of GAD and MDD was determined, using Diagnostic and Statistical Manual of Mental Disorders, Third Edition criteria. RESULTS: In separate regression models adjusting for age and then additionally for place of service, ethnicity, marital status, alcohol consumption, smoking, body mass index, household income, and education grade, both GAD and MDD were related positively to hypertension. In age-adjusted and fully adjusted models comparing comorbid GAD/MDD, GAD alone, MDD alone, and neither condition, comorbidity showed the strongest relationship with hypertension. CONCLUSION: Depression has been the main focus for research on mental health and physical health outcomes. The present results suggest that future research should pay equal attention to GAD and, in particular, the comorbidity of GAD and MDD.

KW - major depression

KW - fasting glucose

KW - comorbidity

KW - veterans

KW - hypertension

KW - diagnosis

KW - Depressive symptoms

KW - generalized anxiety disorder

KW - major depressive disorder

KW - type 2 diabetes

U2 - 10.1097/PSY.0b013e3181c4fca1

DO - 10.1097/PSY.0b013e3181c4fca1

M3 - Article

C2 - 19933507

VL - 72

SP - 16

EP - 19

JO - Psychosomatic Medicine

JF - Psychosomatic Medicine

SN - 0033-3174

IS - 1

ER -