Gamma(delta) T cells: non-classical ligands for non-classical cells

C R Steele; D E Oppenheim; A C Hayday

Gamma(delta) T cells: non-classical ligands for non-classical cells

C R Steele, D E Oppenheim, A C Hayday

Immunology and Immunotherapy

Research output: Contribution to journal › Article

35 Citations (Scopus)

Abstract

A recent study describes direct binding between a gammadelta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (MHC) molecule. A companion study, solving the crystal structure of T22, highlights the differences between this interaction and those of classical MHC molecules and alphabeta T cells.

Original language	English
Pages (from-to)	R282-5
Journal	Current Biology
Volume	10
Issue number	7
Publication status	Published - 6 Apr 2000

Keywords

Crystallography
Histocompatibility Antigens Class I
Models, Immunological
Models, Molecular
Proteins
Receptors, Antigen, T-Cell, gamma-delta
T-Lymphocyte Subsets

Cite this

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title = "Gamma(delta) T cells: non-classical ligands for non-classical cells",

abstract = "A recent study describes direct binding between a gammadelta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (MHC) molecule. A companion study, solving the crystal structure of T22, highlights the differences between this interaction and those of classical MHC molecules and alphabeta T cells.",

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T2 - non-classical ligands for non-classical cells

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AU - Oppenheim, D E

AU - Hayday, A C

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AB - A recent study describes direct binding between a gammadelta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (MHC) molecule. A companion study, solving the crystal structure of T22, highlights the differences between this interaction and those of classical MHC molecules and alphabeta T cells.

KW - Crystallography

KW - Histocompatibility Antigens Class I

KW - Models, Immunological

KW - Models, Molecular

KW - Proteins

KW - Receptors, Antigen, T-Cell, gamma-delta

KW - T-Lymphocyte Subsets

M3 - Article

C2 - 10753741

SN - 0960-9822

VL - 10

SP - R282-5

JO - Current Biology

JF - Current Biology

IS - 7

ER -

Gamma(delta) T cells: non-classical ligands for non-classical cells

Abstract

Keywords

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