Further refinement of the nature of the communication impairment in Cornelia de Lange syndrome: Advances in Mental Health and Intellectual Disabilities

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Abstract

Purpose: Research into the communication skills of individuals with Cornelia de Lange syndrome (CdLS) is extremely limited. This paper aims to evaluate the nature of these skills and impairments in CdLS using a detailed informant assessment of pre-verbal communication skills. Design/methodology/approach: The study used the Pre-verbal Communication Schedule to evaluate communication skills in individuals with CdLS (n=14), aged five to14 years. The group was compared with a contrast group of individuals with Cri du Chat syndrome (CdCS; n=14) who were matched for age and intellectual ability. Findings: A significant difference was identified in understanding non-vocal communication (p

Bibliographic note

Export Date: 23 March 2015 Correspondence Address: Oliver, C.; Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, Birmingham, United Kingdom; email: c.oliver@bham.ac.uk References: Abbeduto, L., Warren, S.F., Conners, F.A., Language development in down syndrome: From the linguistic period to the acquisition of literacy (2007) Mental Retardation and Developmental Disabilities Research Reviews, 13, pp. 247-261; Arron, K., Oliver, C., Berg, K., Moss, J., Burbidge, C., Prevalence and phenomenology of self-injurious and aggressive behaviour in genetic syndromes (2011) Journal of Intellectual Disability Research, 55, pp. 109-120; Arron, K., Oliver, C., Hall, S., Sloneem, J., Forman, D., McClintock, K., Effects of social context on social interaction and self-injurious behavior in Cornelia de Lange syndrome (2006) American Journal on Mental Retardation, 111, pp. 184-192; Baird, G., Cass, H., Slonims, V., Diagnosis of autism (2003) British Medical Journal, 327, pp. 488-493; Bartlett, C., Bunning, K., The importance of communication partnerships: A study to investigate the communicative exchanges between staff and adults with learning disabilities (1997) British Journal of Learning Disabilities, 25, pp. 148-153; Basile, E., Villa, L., Selicorni, A., Molteni, M., The behavioural phenotype of Cornelia de Lange syndrome: A study of 56 individuals (2007) Journal of Intellectual Disability Research, 51, pp. 671-681; Berney, T.P., Ireland, M., Burn, J., Behavioural phenotype of Cornelia de Lange syndrome (1999) Archives of Disease in Childhood, 81, pp. 333-336; Bradshaw, J., Complexity of staff communication and reported level of understanding of skills in adults with intellectual disability (2001) Journal of Disability Research, 45 (3), pp. 233-243; Brady, N.C., Marquis, J., Fleming, K., McLean, L., Prelinguistic predictors of language growth in children with developmental disabilities (2004) Journal of Speech, Language and Hearing Research, 47, pp. 663-677; Charman, T., Baron-Cohen, S., Swettenham, J., Baird, G., Cox, A., Drew, A., Testing joint attention, imitation and play as infancy precursors to language and theory of mind (2000) Cognitive Development, 15, pp. 481-498; Collins, M., Cornish, K.M., A survey of the prevalence of stereotypy, self-injury and aggression in children and young adults with Cri-du-Chat syndrome (2002) Journal of Intellectual Disabilities Research, 46, pp. 133-140; Collis, L., Oliver, C., Moss, J., Low mood and social anxiety in Cornelia de Lange syndrome (2006) Journal of Intellectual Disability Research, 50, pp. 791-800; Cornish, K., Pigram, J., Developmental and behavioral characteristics of cir-du-chat syndrome (1996) Archives of Disease in Childhood, 75, pp. 448-450; Cornish, K., Munir, F., Bramble, D., Adaptive and maladaptive behaviour in children with Cri-du-chat syndrome (1998) Journal of Applied Research in Intellectual Disabilities, 11, pp. 239-246; Cornish, K.M., Bramble, D., Annotation: Cri-du-Chat syndrome: From genotype to phenotype and implication for clinical management (2002) Developmental Medicine and Child Neurology, 44, pp. 494-497; Cornish, K.M., Munir, F., Receptive and expressive language skills in children with Cri-du-Chat syndrome (1998) Journal of Communication Disorders, 31, pp. 73-81; Cornish, K.M., Bramble, D., Munir, F., Pigram, J., Cognitive functioning in children with typical Cri du Chat (5p-) syndrome (1999) Developmental Medicine and Child Neurology, 41, pp. 263-266; Cornish, K.M., Turk, J., Levitas, A., Fragile X syndrome and autism: Common developmental pathways? 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Details

Original languageEnglish
Pages (from-to)15-25
Number of pages11
JournalAdvances in Mental Health and Intellectual Disabilities
Volume5
Issue number4
Publication statusPublished - 2011

Keywords

  • Behaviour, Chromosomes, Communication, Cornelia de Lange syndrome, Cri du Chat syndrome, Genetic syndromes, Phenotypes, Speech