TY - JOUR
T1 - Fructose and Galactose Enhance Post-Exercise Human Liver Glycogen Synthesis.
AU - Décombaz, J
AU - Jentjens, R
AU - Ith, M
AU - Scheurer, E
AU - Buehler, T
AU - Jeukendrup, Asker
AU - Boesch, C
PY - 2011/3/10
Y1 - 2011/3/10
N2 - PURPOSE:: Both liver and muscle glycogen stores play a fundamental role in exercise and fatigue, but the effect of different carbohydrate (CHO) sources on liver glycogen synthesis in humans is unclear. The aim was to compare the effect of maltodextrin (MD) drinks containing galactose, fructose or glucose on post-exercise liver glycogen synthesis. METHODS:: In this double blind, triple cross-over, randomized clinical trial 10 well-trained male cyclists performed 3 experimental exercise sessions separated by at least 1 wk. After performing a standard exercise protocol to exhaustion, subjects ingested one of three 15% CHO solutions: FRU (MD+fructose 2:1), GAL (MD+galactose 2:1) or GLU (MD+glucose 2:1), each providing 69 g CHO·h during 6.5 h recovery. Liver glycogen changes were followed using C-magnetic resonance spectroscopy. RESULTS:: Liver glycogen concentration increased at faster rates with FRU (24 ± 2 mmol·L·h; P
AB - PURPOSE:: Both liver and muscle glycogen stores play a fundamental role in exercise and fatigue, but the effect of different carbohydrate (CHO) sources on liver glycogen synthesis in humans is unclear. The aim was to compare the effect of maltodextrin (MD) drinks containing galactose, fructose or glucose on post-exercise liver glycogen synthesis. METHODS:: In this double blind, triple cross-over, randomized clinical trial 10 well-trained male cyclists performed 3 experimental exercise sessions separated by at least 1 wk. After performing a standard exercise protocol to exhaustion, subjects ingested one of three 15% CHO solutions: FRU (MD+fructose 2:1), GAL (MD+galactose 2:1) or GLU (MD+glucose 2:1), each providing 69 g CHO·h during 6.5 h recovery. Liver glycogen changes were followed using C-magnetic resonance spectroscopy. RESULTS:: Liver glycogen concentration increased at faster rates with FRU (24 ± 2 mmol·L·h; P
U2 - 10.1249/MSS.0b013e318218ca5a
DO - 10.1249/MSS.0b013e318218ca5a
M3 - Article
C2 - 21407126
SN - 1530-0315
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
ER -