Frequency and impact of extracolonic findings detected at computed tomographic colonography in a symptomatic population

Research output: Contribution to journalArticle

Standard

Frequency and impact of extracolonic findings detected at computed tomographic colonography in a symptomatic population. / Khan, KY; Xiong, Tengbin; McCafferty, I; Riley, P; Ismail, Tariq; Lilford, Richard; Morton, Dion.

In: British Journal of Surgery, Vol. 94, No. 3, 01.03.2007, p. 355-361.

Research output: Contribution to journalArticle

Harvard

APA

Vancouver

Author

Bibtex

@article{7494b516b8384359be5dc77e911bbcb0,
title = "Frequency and impact of extracolonic findings detected at computed tomographic colonography in a symptomatic population",
abstract = "BACKGROUND: Extracolonic findings are frequently recognized alongside colonic pathology at computed tomographic colonography (CTC). This study assessed the clinical impact of extracolonic findings in a symptomatic population at high risk of colorectal cancer. METHODS: CTC was performed in a consecutive cohort of patients assessed in a fast-track colorectal cancer clinic as being at high risk of colorectal cancer. A review of CTC findings and case notes was undertaken. Patients with extracolonic findings were followed up for at least 12 months. RESULTS: Thirty-one (13.8 per cent) of 225 patients investigated by CTC had colorectal cancer. Extracolonic findings were identified in 81 (53.3 per cent) of 152 patients with normal or non-neoplastic bowel findings, compared with 27 (37 per cent) of 73 patients with colorectal neoplasia (P = 0.025). Twenty-four patients (10.7 per cent) with extracolonic findings underwent further investigation or treatment. The median duration of investigation was 19.5 weeks. Seventy-five clinical events were recorded, including 14 surgical procedures. CONCLUSION: A prospective cost-benefit analysis of diagnostic CTC should be performed before it is established as a first-line investigation for colonic symptoms.",
author = "KY Khan and Tengbin Xiong and I McCafferty and P Riley and Tariq Ismail and Richard Lilford and Dion Morton",
year = "2007",
month = mar,
day = "1",
doi = "10.1002/bjs.5498",
language = "English",
volume = "94",
pages = "355--361",
journal = "British Journal of Surgery",
issn = "0007-1323",
publisher = "Wiley",
number = "3",

}

RIS

TY - JOUR

T1 - Frequency and impact of extracolonic findings detected at computed tomographic colonography in a symptomatic population

AU - Khan, KY

AU - Xiong, Tengbin

AU - McCafferty, I

AU - Riley, P

AU - Ismail, Tariq

AU - Lilford, Richard

AU - Morton, Dion

PY - 2007/3/1

Y1 - 2007/3/1

N2 - BACKGROUND: Extracolonic findings are frequently recognized alongside colonic pathology at computed tomographic colonography (CTC). This study assessed the clinical impact of extracolonic findings in a symptomatic population at high risk of colorectal cancer. METHODS: CTC was performed in a consecutive cohort of patients assessed in a fast-track colorectal cancer clinic as being at high risk of colorectal cancer. A review of CTC findings and case notes was undertaken. Patients with extracolonic findings were followed up for at least 12 months. RESULTS: Thirty-one (13.8 per cent) of 225 patients investigated by CTC had colorectal cancer. Extracolonic findings were identified in 81 (53.3 per cent) of 152 patients with normal or non-neoplastic bowel findings, compared with 27 (37 per cent) of 73 patients with colorectal neoplasia (P = 0.025). Twenty-four patients (10.7 per cent) with extracolonic findings underwent further investigation or treatment. The median duration of investigation was 19.5 weeks. Seventy-five clinical events were recorded, including 14 surgical procedures. CONCLUSION: A prospective cost-benefit analysis of diagnostic CTC should be performed before it is established as a first-line investigation for colonic symptoms.

AB - BACKGROUND: Extracolonic findings are frequently recognized alongside colonic pathology at computed tomographic colonography (CTC). This study assessed the clinical impact of extracolonic findings in a symptomatic population at high risk of colorectal cancer. METHODS: CTC was performed in a consecutive cohort of patients assessed in a fast-track colorectal cancer clinic as being at high risk of colorectal cancer. A review of CTC findings and case notes was undertaken. Patients with extracolonic findings were followed up for at least 12 months. RESULTS: Thirty-one (13.8 per cent) of 225 patients investigated by CTC had colorectal cancer. Extracolonic findings were identified in 81 (53.3 per cent) of 152 patients with normal or non-neoplastic bowel findings, compared with 27 (37 per cent) of 73 patients with colorectal neoplasia (P = 0.025). Twenty-four patients (10.7 per cent) with extracolonic findings underwent further investigation or treatment. The median duration of investigation was 19.5 weeks. Seventy-five clinical events were recorded, including 14 surgical procedures. CONCLUSION: A prospective cost-benefit analysis of diagnostic CTC should be performed before it is established as a first-line investigation for colonic symptoms.

U2 - 10.1002/bjs.5498

DO - 10.1002/bjs.5498

M3 - Article

C2 - 17262750

VL - 94

SP - 355

EP - 361

JO - British Journal of Surgery

JF - British Journal of Surgery

SN - 0007-1323

IS - 3

ER -