Fractal analysis of mucosal microvascular patterns in oral lichen planus: A preliminary study

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Fractal analysis of mucosal microvascular patterns in oral lichen planus : A preliminary study. / Lucchese, Alberta; Gentile, Enrica; Capone, Giovanni; De Vico, Gionata; Serpico, Rosario; Landini, Gabriel.

In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 120, No. 5, 11.2015, p. 609-615.

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Lucchese, Alberta ; Gentile, Enrica ; Capone, Giovanni ; De Vico, Gionata ; Serpico, Rosario ; Landini, Gabriel. / Fractal analysis of mucosal microvascular patterns in oral lichen planus : A preliminary study. In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2015 ; Vol. 120, No. 5. pp. 609-615.

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@article{3bba9905786b4123a9f4294536bb77a4,
title = "Fractal analysis of mucosal microvascular patterns in oral lichen planus: A preliminary study",
abstract = "Objectives: The objective of this study was to assess local vascular architecture in atrophic-erosive oral lichen planus (OLP). Materials and Methods: We investigated the capillary structure of the oral mucosa in 31 patients with OLP and 32 healthy controls. Capillaries images were captured invivo through a capillaroscope. We applied fractal analysis to quantify the microvasculature morphometric changes in the oral mucosa of atrophic-erosive OLP patients in terms of their fractal dimension (D). Results: The oral vascular networks of atrophic-erosive OLP lesions had a significantly higher D, both in buccal mucosae (D=1.167, P= .019) and in tongue (D= 1.196, P= .038), compared with the control population (1.123 for both locations, respectively). Conclusions: The present study confirms previous literature data on a close relationship between abnormal vascular architecture and atrophic-erosive OLP. Fractal analysis provided a quantitative descriptor of the complexity of the vascular patterns, which increases in the OLP samples. These data may provide new information on the OLP pathogenesis, as well as serve as morphologic quantifiers for monitoring treatment strategies.",
author = "Alberta Lucchese and Enrica Gentile and Giovanni Capone and {De Vico}, Gionata and Rosario Serpico and Gabriel Landini",
year = "2015",
month = nov,
doi = "10.1016/j.oooo.2015.06.029",
language = "English",
volume = "120",
pages = "609--615",
journal = "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology",
issn = "2212-4403",
publisher = "Elsevier",
number = "5",

}

RIS

TY - JOUR

T1 - Fractal analysis of mucosal microvascular patterns in oral lichen planus

T2 - A preliminary study

AU - Lucchese, Alberta

AU - Gentile, Enrica

AU - Capone, Giovanni

AU - De Vico, Gionata

AU - Serpico, Rosario

AU - Landini, Gabriel

PY - 2015/11

Y1 - 2015/11

N2 - Objectives: The objective of this study was to assess local vascular architecture in atrophic-erosive oral lichen planus (OLP). Materials and Methods: We investigated the capillary structure of the oral mucosa in 31 patients with OLP and 32 healthy controls. Capillaries images were captured invivo through a capillaroscope. We applied fractal analysis to quantify the microvasculature morphometric changes in the oral mucosa of atrophic-erosive OLP patients in terms of their fractal dimension (D). Results: The oral vascular networks of atrophic-erosive OLP lesions had a significantly higher D, both in buccal mucosae (D=1.167, P= .019) and in tongue (D= 1.196, P= .038), compared with the control population (1.123 for both locations, respectively). Conclusions: The present study confirms previous literature data on a close relationship between abnormal vascular architecture and atrophic-erosive OLP. Fractal analysis provided a quantitative descriptor of the complexity of the vascular patterns, which increases in the OLP samples. These data may provide new information on the OLP pathogenesis, as well as serve as morphologic quantifiers for monitoring treatment strategies.

AB - Objectives: The objective of this study was to assess local vascular architecture in atrophic-erosive oral lichen planus (OLP). Materials and Methods: We investigated the capillary structure of the oral mucosa in 31 patients with OLP and 32 healthy controls. Capillaries images were captured invivo through a capillaroscope. We applied fractal analysis to quantify the microvasculature morphometric changes in the oral mucosa of atrophic-erosive OLP patients in terms of their fractal dimension (D). Results: The oral vascular networks of atrophic-erosive OLP lesions had a significantly higher D, both in buccal mucosae (D=1.167, P= .019) and in tongue (D= 1.196, P= .038), compared with the control population (1.123 for both locations, respectively). Conclusions: The present study confirms previous literature data on a close relationship between abnormal vascular architecture and atrophic-erosive OLP. Fractal analysis provided a quantitative descriptor of the complexity of the vascular patterns, which increases in the OLP samples. These data may provide new information on the OLP pathogenesis, as well as serve as morphologic quantifiers for monitoring treatment strategies.

UR - http://www.scopus.com/inward/record.url?scp=84940055320&partnerID=8YFLogxK

U2 - 10.1016/j.oooo.2015.06.029

DO - 10.1016/j.oooo.2015.06.029

M3 - Article

VL - 120

SP - 609

EP - 615

JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

SN - 2212-4403

IS - 5

ER -