Exploring roll compaction of two commonly used pharmaceutical powders

Research output: Contribution to journalArticle


  • Shen Yu
  • B Gururajan
  • G Reynolds
  • R Roberts

Colleges, School and Institutes


The effect of powder flow properties on roll compaction behaviour of microcrystalline cellulose (MCC) and di-calcium phosphate dihydrate (DCPD), which have distinctive flow properties, was experimentally investigated. A robust approach for determining the nip angle that defines the compaction region was also developed. It was found that powder flow properties play a significant role in roll compaction.


Original languageEnglish
Pages (from-to)1434-1435
Number of pages2
JournalJournal of Pharmacy and Pharmacology
Issue number10
Publication statusPublished - 1 Oct 2010