Exploitation of the Escherichia coli lac operon promoter for controlled recombinant protein production
Research output: Contribution to journal › Review article › peer-review
Colleges, School and Institutes
- University of Birmingham
- School of Biosciences, University of Kent, Ingram Building, Canterbury CT2 7NJ, U.K.
The Escherichia coli lac operon promoter is widely used as a tool to control recombinant protein production in bacteria. Here, we give a brief review of how it functions, how it is regulated, and how, based on this knowledge, a suite of lac promoter derivatives has been developed to give a controlled expression that is suitable for diverse biotechnology applications.
|Number of pages||9|
|Journal||Biochemical Society Transactions|
|Early online date||10 Apr 2019|
|Publication status||Published - 30 Apr 2019|
- Escherichia coli/genetics, Lac Operon/genetics, Promoter Regions, Genetic/genetics, Recombinant Proteins/genetics, Repressor Proteins/genetics, Transcription, Genetic/genetics