Projects per year
Abstract
Idiopathic intracranial hypertension (IIH) is a rare but important disease associated with significant morbidity. There is an expected rise in prevalence in line with the escalating global burden of obesity. Modern revisions in the terminology and diagnostic criteria for IIH help guide clinicians in investigations and researchers in standardising recruitment criteria for clinical trials. The pathophysiology of IIH is incompletely characterised; suggested underpinning mechanisms include the role of cerebrospinal fluid regulation as well as metabolic and endocrinological perspectives. Recent treatment trials are providing insights into the management but debate still surrounds key areas in treatment. This review will provide an up-to-date discussion on the potential pathogenic mechanisms and management of IIH.
Original language | English |
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Pages (from-to) | 982-992 |
Journal | Journal of Neurology Neurosurgery and Psychiatry |
Volume | 87 |
Issue number | 9 |
Early online date | 17 Feb 2016 |
DOIs | |
Publication status | Published - Sept 2016 |
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Dive into the research topics of 'Evolving evidence in adult idiopathic intracranial hypertension: pathophysiology and management'. Together they form a unique fingerprint.Projects
- 1 Finished
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Assessing the Therapeutic Efficacy of an 11Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) in Idiopathic Intracranial Hypertension (IIH)
Sinclair, A., Tomlinson, J. & Stewart, P.
12/08/13 → 11/08/17
Project: Research Councils