Evaluation of a transient, simultaneous, arbitrary Lagrange-Euler based multi-physics method for simulating the mitral heart valve

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@article{cd66c669dd6b410e8ca6fce7b3786265,
title = "Evaluation of a transient, simultaneous, arbitrary Lagrange-Euler based multi-physics method for simulating the mitral heart valve",
abstract = "A transient multi-physics model of the mitral heart valve has been developed, which allows simultaneous calculation of fluid flow and structural deformation. A recently developed contact method has been applied to enable simulation of systole (the stage when blood pressure is elevated within the heart to pump blood to the body). The geometry was simplified to represent the mitral valve within the heart walls in two dimensions. Only the mitral valve undergoes deformation. A moving arbitrary Lagrange-Euler mesh is used to allow true fluid-structure interaction (FSI). The FSI model requires blood flow to induce valve closure by inducing strains in the region of 10-20%. Model predictions were found to be consistent with existing literature and will undergo further development.",
author = "Espino, {Daniel M} and Shepherd, {Duncan E T} and Hukins, {David W L}",
year = "2014",
doi = "10.1080/10255842.2012.688818",
language = "English",
volume = "17",
pages = "450--458",
journal = "Computer Methods in Biomechanics and Biomedical Engineering",
issn = "1025-5842",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - Evaluation of a transient, simultaneous, arbitrary Lagrange-Euler based multi-physics method for simulating the mitral heart valve

AU - Espino, Daniel M

AU - Shepherd, Duncan E T

AU - Hukins, David W L

PY - 2014

Y1 - 2014

N2 - A transient multi-physics model of the mitral heart valve has been developed, which allows simultaneous calculation of fluid flow and structural deformation. A recently developed contact method has been applied to enable simulation of systole (the stage when blood pressure is elevated within the heart to pump blood to the body). The geometry was simplified to represent the mitral valve within the heart walls in two dimensions. Only the mitral valve undergoes deformation. A moving arbitrary Lagrange-Euler mesh is used to allow true fluid-structure interaction (FSI). The FSI model requires blood flow to induce valve closure by inducing strains in the region of 10-20%. Model predictions were found to be consistent with existing literature and will undergo further development.

AB - A transient multi-physics model of the mitral heart valve has been developed, which allows simultaneous calculation of fluid flow and structural deformation. A recently developed contact method has been applied to enable simulation of systole (the stage when blood pressure is elevated within the heart to pump blood to the body). The geometry was simplified to represent the mitral valve within the heart walls in two dimensions. Only the mitral valve undergoes deformation. A moving arbitrary Lagrange-Euler mesh is used to allow true fluid-structure interaction (FSI). The FSI model requires blood flow to induce valve closure by inducing strains in the region of 10-20%. Model predictions were found to be consistent with existing literature and will undergo further development.

U2 - 10.1080/10255842.2012.688818

DO - 10.1080/10255842.2012.688818

M3 - Article

C2 - 22640492

VL - 17

SP - 450

EP - 458

JO - Computer Methods in Biomechanics and Biomedical Engineering

JF - Computer Methods in Biomechanics and Biomedical Engineering

SN - 1025-5842

IS - 4

ER -