Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress

Research output: Contribution to journalArticle

Authors

  • Sjon Hartman
  • Zeguang Liu
  • Hans van Veen
  • Jorge Vicente
  • Emilie Reinen
  • Shanice Martopawiro
  • Hongtao Zhang
  • Nienke van Dongen
  • Femke Bosman
  • Eric J W Visser
  • Julia Bailey-Serres
  • Frederica L Theodoulou
  • Kim H Hebelstrup
  • Michael J Holdsworth
  • Rashmi Sasidharan
  • Laurentius A C J Voesenek

Colleges, School and Institutes

External organisations

  • Plant Ecophysiology, Institute of Environmental Biology, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • School of Biosciences, University of Nottingham, Loughborough, LE12 5RD, UK.
  • Plant Sciences Department, Rothamsted Research, Harpenden, AL5 2JQ, UK.
  • Department of Experimental Plant Ecology, Institute for Water and Wetland Research, Radboud University Nijmegen, 6525 AJ, Nijmegen, the Netherlands.
  • Botany and Plant Sciences Department and Center for Plant Cell Biology, University of California, Riverside, CA, 92521, USA.
  • Department of Molecular Biology and Genetics, Aarhus University, Forsøgsvej 1, DK-4200, Slagelse, Denmark.
  • School of Biosciences, University of Nottingham, Loughborough, LE12 5RD, UK. Michael.Holdsworth@nottingham.ac.uk.
  • Plant Ecophysiology, Institute of Environmental Biology, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands. R.sasidharan@uu.nl.
  • Plant Ecophysiology, Institute of Environmental Biology, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands. L.a.c.j.voesenek@uu.nl.

Abstract

Timely perception of adverse environmental changes is critical for survival. Dynamic changes in gases are important cues for plants to sense environmental perturbations, such as submergence. In Arabidopsis thaliana, changes in oxygen and nitric oxide (NO) control the stability of ERFVII transcription factors. ERFVII proteolysis is regulated by the N-degron pathway and mediates adaptation to flooding-induced hypoxia. However, how plants detect and transduce early submergence signals remains elusive. Here we show that plants can rapidly detect submergence through passive ethylene entrapment and use this signal to pre-adapt to impending hypoxia. Ethylene can enhance ERFVII stability prior to hypoxia by increasing the NO-scavenger PHYTOGLOBIN1. This ethylene-mediated NO depletion and consequent ERFVII accumulation pre-adapts plants to survive subsequent hypoxia. Our results reveal the biological link between three gaseous signals for the regulation of flooding survival and identifies key regulatory targets for early stress perception that could be pivotal for developing flood-tolerant crops.

Details

Original languageEnglish
Article number4020
Number of pages9
JournalNature Communications
Volume10
Issue number1
Publication statusPublished - 5 Sep 2019