Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis in Adults Characterized by High Viral Genome Load within Circulating Natural Killer Cells

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@article{6b9d3cfc919a47eeb2913f9f5b05f733,
title = "Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis in Adults Characterized by High Viral Genome Load within Circulating Natural Killer Cells",
abstract = "Epstein-Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis (HLH) is a rare and aggressive disease usually encountered in the context of primary EBV infection. In most analyzed cases, EBV has been found predominantly in T cells. We describe the novel finding of high EBV genome numbers within circulating natural killer cells in adult patients with EBV-HLH.",
author = "Christopher Fox and Claire Shannon-Lowe and P Gothard and B Kishore and J Neilson and N O'Connor and Martin Rowe",
year = "2010",
month = jul
day = "1",
doi = "10.1086/653424",
language = "English",
volume = "51",
pages = "66--69",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "1",

}

RIS

TY - JOUR

T1 - Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis in Adults Characterized by High Viral Genome Load within Circulating Natural Killer Cells

AU - Fox, Christopher

AU - Shannon-Lowe, Claire

AU - Gothard, P

AU - Kishore, B

AU - Neilson, J

AU - O'Connor, N

AU - Rowe, Martin

PY - 2010/7/1

Y1 - 2010/7/1

N2 - Epstein-Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis (HLH) is a rare and aggressive disease usually encountered in the context of primary EBV infection. In most analyzed cases, EBV has been found predominantly in T cells. We describe the novel finding of high EBV genome numbers within circulating natural killer cells in adult patients with EBV-HLH.

AB - Epstein-Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis (HLH) is a rare and aggressive disease usually encountered in the context of primary EBV infection. In most analyzed cases, EBV has been found predominantly in T cells. We describe the novel finding of high EBV genome numbers within circulating natural killer cells in adult patients with EBV-HLH.

U2 - 10.1086/653424

DO - 10.1086/653424

M3 - Article

C2 - 20504238

VL - 51

SP - 66

EP - 69

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - 1

ER -