Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis in Adults Characterized by High Viral Genome Load within Circulating Natural Killer Cells

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Epstein-Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis (HLH) is a rare and aggressive disease usually encountered in the context of primary EBV infection. In most analyzed cases, EBV has been found predominantly in T cells. We describe the novel finding of high EBV genome numbers within circulating natural killer cells in adult patients with EBV-HLH.


Original languageEnglish
Pages (from-to)66-69
Number of pages4
JournalClinical Infectious Diseases
Issue number1
Publication statusPublished - 1 Jul 2010