Epstein-Barr virus: more than 50 years old and still providing surprises

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Epstein-Barr virus : more than 50 years old and still providing surprises. / Young, Lawrence S; Yap, Lee Fah; Murray, Paul G.

In: Nature Reviews Cancer, Vol. 16, No. 12, 01.12.2016, p. 789-802.

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Young, Lawrence S ; Yap, Lee Fah ; Murray, Paul G. / Epstein-Barr virus : more than 50 years old and still providing surprises. In: Nature Reviews Cancer. 2016 ; Vol. 16, No. 12. pp. 789-802.

Bibtex

@article{634fe7e423264f4baa1ea077087736dc,
title = "Epstein-Barr virus: more than 50 years old and still providing surprises",
abstract = "It is more than 50 years since the Epstein-Barr virus (EBV), the first human tumour virus, was discovered. EBV has subsequently been found to be associated with a diverse range of tumours of both lymphoid and epithelial origin. Progress in the molecular analysis of EBV has revealed fundamental mechanisms of more general relevance to the oncogenic process. This Timeline article highlights key milestones in the 50-year history of EBV and discusses how this virus provides a paradigm for exploiting insights at the molecular level in the diagnosis, treatment and prevention of cancer.",
keywords = "Epstein-Barr Virus Infections/virology, Herpesvirus 4, Human/physiology, History, 20th Century, History, 21st Century, Humans, Lymphoma/virology, Neoplasms, Glandular and Epithelial/virology",
author = "Young, {Lawrence S} and Yap, {Lee Fah} and Murray, {Paul G}",
year = "2016",
month = dec,
day = "1",
doi = "10.1038/nrc.2016.92",
language = "English",
volume = "16",
pages = "789--802",
journal = "Nature Reviews Cancer",
issn = "1474-175X",
publisher = "Nature Publishing Group",
number = "12",

}

RIS

TY - JOUR

T1 - Epstein-Barr virus

T2 - more than 50 years old and still providing surprises

AU - Young, Lawrence S

AU - Yap, Lee Fah

AU - Murray, Paul G

PY - 2016/12/1

Y1 - 2016/12/1

N2 - It is more than 50 years since the Epstein-Barr virus (EBV), the first human tumour virus, was discovered. EBV has subsequently been found to be associated with a diverse range of tumours of both lymphoid and epithelial origin. Progress in the molecular analysis of EBV has revealed fundamental mechanisms of more general relevance to the oncogenic process. This Timeline article highlights key milestones in the 50-year history of EBV and discusses how this virus provides a paradigm for exploiting insights at the molecular level in the diagnosis, treatment and prevention of cancer.

AB - It is more than 50 years since the Epstein-Barr virus (EBV), the first human tumour virus, was discovered. EBV has subsequently been found to be associated with a diverse range of tumours of both lymphoid and epithelial origin. Progress in the molecular analysis of EBV has revealed fundamental mechanisms of more general relevance to the oncogenic process. This Timeline article highlights key milestones in the 50-year history of EBV and discusses how this virus provides a paradigm for exploiting insights at the molecular level in the diagnosis, treatment and prevention of cancer.

KW - Epstein-Barr Virus Infections/virology

KW - Herpesvirus 4, Human/physiology

KW - History, 20th Century

KW - History, 21st Century

KW - Humans

KW - Lymphoma/virology

KW - Neoplasms, Glandular and Epithelial/virology

U2 - 10.1038/nrc.2016.92

DO - 10.1038/nrc.2016.92

M3 - Review article

C2 - 27687982

VL - 16

SP - 789

EP - 802

JO - Nature Reviews Cancer

JF - Nature Reviews Cancer

SN - 1474-175X

IS - 12

ER -