Electron capture dissociation in the analysis of protein phosphorylation

Research output: Contribution to journalReview article

Colleges, School and Institutes

Abstract

Protein phosphorylation is a widespread and important post-translational modification. Despite recent advances in phosphoproteomic methods, phosphopeptide identification and site localization remain challenging. Electron capture dissociation has inherent advantages for phosphorylation analysis. The use of electron capture dissociation in this area to date is reviewed and future prospects are outlined.

Details

Original languageEnglish
Pages (from-to)149-159
Number of pages11
JournalExpert Review of Proteomics
Volume4
Issue number2
Publication statusPublished - 1 Apr 2007