Electrochemical Method for the Determination of Enantiomeric Excess of Binol Using Redox-Active Boronic Acids as Chiral Sensors

Research output: Contribution to journalArticle

Authors

  • Giorgio Mirri
  • SD Bull
  • PN Horton
  • TD James
  • Louise Male

Colleges, School and Institutes

Abstract

A chiral ferrocene-based boronic acid interacts with (R)- and (S)-Binol to form two complexes that exhibit significantly different. ferrocene-based electrode potentials. This difference in redox behavior can be exploited to demonstrate in principle how high levels of enantiomeric excess in a mixture of enantiomers can be quantified and read-out using an electrochemical method.

Details

Original languageEnglish
Pages (from-to)8903-+
JournalJournal of the American Chemical Society
Volume132
Issue number26
Publication statusPublished - 1 Jul 2010