Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes

Research output: Contribution to journalArticle

Authors

  • F. J. Rawson
  • M. T. Cole
  • J. M. Hicks
  • J. W. Aylott
  • W. I. Milne
  • C. M. Collins
  • S. K. Jackson
  • N. J. Silman

Colleges, School and Institutes

External organisations

  • University of Nottingham
  • University of Cambridge
  • Plymouth University
  • Public Health England

Abstract

With the rapidly increasing demands for ultrasensitive biodetection, the design and applications of new nano-scale materials for development of sensors based on optical and electrochemical transducers have attracted substantial interest. In particular, given the comparable sizes of nanomaterials and biomolecules, there exist plenty of opportunities to develop functional nanoprobes with biomolecules for highly sensitive and selective biosensing, shedding new light on cellular behaviour. Towards this aim, herein we interface cells with patterned nano-arrays of carbon nanofibers forming a nanosensor-cell construct. We show that such a construct is capable of electrochemically communicating with the intracellular environment.

Details

Original languageEnglish
Article number37672
JournalScientific Reports
Volume6
Publication statusPublished - 1 Dec 2016

ASJC Scopus subject areas