Efflux in Acinetobacter baumannii can be determined by measuring accumulation of H33342 (bis-benzamide)
Research output: Contribution to journal › Article
Colleges, School and Institutes
Overexpression of efflux pumps in Acinetobacter baumannii is a common mechanism of multidrug resistance in this nosocomial pathogen. Increased efflux pump expression is often assumed from MICs of antibiotics and dyes, without measurement of efflux levels. This study describes a safe, rapid and simple 96-well plate assay that measures the accumulation of a fluorescent dye, Hoechst (H) 33342.
|Number of pages||7|
|Journal||Journal of Antimicrobial Chemotherapy|
|Publication status||Published - Jul 2013|