Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT
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Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT. / Parretti, Helen; Aveyard, Paul; Blannin, Andrew; Clifford, Susan; Coleman, Sarah; Roalfe, Andrea; Daley, Amanda.
In: Obesity, Vol. 23, No. 9, 01.09.2015, p. 1785-1791.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity:
T2 - RCT
AU - Parretti, Helen
AU - Aveyard, Paul
AU - Blannin, Andrew
AU - Clifford, Susan
AU - Coleman, Sarah
AU - Roalfe, Andrea
AU - Daley, Amanda
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Objective: To investigate the efficacy of water preloading before meals as a weight loss strategy for adults with obesity. Methods: Two group randomized controlled trial conducted in Birmingham, England. 84 adults with obesity were recruited from general practices. All participants were given a face to face weight management consultation at baseline (30 minutes) and a follow-up telephone consultation at two weeks (10 minutes). At baseline participants were randomized to either drinking 500mls of water 30 minutes before their main meals or an attention control group where participants were asked to imagine their stomach was full before meals. The primary outcome was weight change at 12 weeks follow up. Several measures of adherence were also used, including 24hr total urine collections. Results: 41 participants were randomized to the intervention group and 43 to the comparator group. The water preloading group lost -1.3kg (95% CI -2.4 to -0.1, p=0.028) more than comparators at follow up. Adjusting for ethnicity, deprivation, age and gender resulted in the intervention group losing -1.2kg (95% CI -2.4 to 0.07, p=0.063) more than the comparator. Conclusion: There is preliminary evidence that water preloading before main meals leads to a moderate weight loss at follow up. ISRCTN33238158
AB - Objective: To investigate the efficacy of water preloading before meals as a weight loss strategy for adults with obesity. Methods: Two group randomized controlled trial conducted in Birmingham, England. 84 adults with obesity were recruited from general practices. All participants were given a face to face weight management consultation at baseline (30 minutes) and a follow-up telephone consultation at two weeks (10 minutes). At baseline participants were randomized to either drinking 500mls of water 30 minutes before their main meals or an attention control group where participants were asked to imagine their stomach was full before meals. The primary outcome was weight change at 12 weeks follow up. Several measures of adherence were also used, including 24hr total urine collections. Results: 41 participants were randomized to the intervention group and 43 to the comparator group. The water preloading group lost -1.3kg (95% CI -2.4 to -0.1, p=0.028) more than comparators at follow up. Adjusting for ethnicity, deprivation, age and gender resulted in the intervention group losing -1.2kg (95% CI -2.4 to 0.07, p=0.063) more than the comparator. Conclusion: There is preliminary evidence that water preloading before main meals leads to a moderate weight loss at follow up. ISRCTN33238158
KW - weight loss
KW - clinical trials
KW - primary care
KW - obesity
U2 - 10.1002/oby.21167
DO - 10.1002/oby.21167
M3 - Article
VL - 23
SP - 1785
EP - 1791
JO - Obesity
JF - Obesity
SN - 1930-7381
IS - 9
ER -