Effects of Social Interaction on Pragmatic Communication and Self-Injurious Behavior in Cornelia de Lange syndrome

Research output: Contribution to journalArticle

Authors

  • S Hall
  • Jennifer Sloneem
  • D Forman
  • K McClintock

Colleges, School and Institutes

Abstract

Cornelia de Lange syndrome is reported to be associated with self-injurious behavior (SIB) and social avoidance. We used analog methodology to examine the effect of manipulating adult social contact on social communicative behaviors and SIB in 16 children with this syndrome. For 9 participants engagement behavior was related to levels of adult attention, and SIB showed significant variability across conditions for 3 participants. These findings indicate that SIB can be affected by environmental factors, even though it is thought to be part of the behavioral phenotype of Cornelia de Lange syndrome and suggest that individuals with this syndrome show socially motivated attention-soliciting behaviors. The implications for gene-environment interactions are discussed.

Details

Original languageEnglish
Pages (from-to)184-192
Number of pages9
JournalAmerican Journal on Mental Retardation
Volume111
Publication statusPublished - 1 Jan 2006