TY - JOUR
T1 - Effects of on forearm vasculature in treated chronic heart failure
AU - Gunaruwan, Prasad
AU - Schmitt, M
AU - Sharman, J
AU - Frenneaux, Michael
PY - 2005/2/1
Y1 - 2005/2/1
N2 - The nongenomic effects of aldosterone in disease states associated with endothelial dysfunction may differ from those in healthy subjects. The effects of locally infused aldosterone on the forearm blood flow and volume were studied in optimally treated patients with chronic heart failure (CHF). At baseline and after incremental intrabrachial aldosterone, forearm blood flow was assessed using conventional strain gauge plethysmography, and forearm venous volume was assessed by radionuclide plethysmography. Constriction of the resistance vasculature of the forearm without significant effect on forearm venous capacitance was demonstrated in response to aldosterone in patients treated for CHF.
AB - The nongenomic effects of aldosterone in disease states associated with endothelial dysfunction may differ from those in healthy subjects. The effects of locally infused aldosterone on the forearm blood flow and volume were studied in optimally treated patients with chronic heart failure (CHF). At baseline and after incremental intrabrachial aldosterone, forearm blood flow was assessed using conventional strain gauge plethysmography, and forearm venous volume was assessed by radionuclide plethysmography. Constriction of the resistance vasculature of the forearm without significant effect on forearm venous capacitance was demonstrated in response to aldosterone in patients treated for CHF.
UR - http://www.scopus.com/inward/record.url?scp=12844249484&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2004.09.047
DO - 10.1016/j.amjcard.2004.09.047
M3 - Article
C2 - 15670558
SN - 1879-1913
VL - 95
SP - 412
EP - 414
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 3
ER -