Effective--a database of predicted secreted bacterial proteins

Research output: Contribution to journalArticlepeer-review

Authors

Colleges, School and Institutes

External organisations

  • Technische Universität München

Abstract

Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins ('effectors') crucial for understanding the molecular bacterium-host interactions. Effective (http://effectors.org) is a database of predicted bacterial secreted proteins, implementing two complementary prediction strategies for protein secretion: the identification of eukaryotic-like protein domains and the recognition of signal peptides in amino acid sequences. The Effective web portal provides user-friendly tools for browsing and retrieving comprehensive precalculated predictions for whole bacterial genomes as well as for the interactive prediction of effectors in user-provided protein sequences.

Details

Original languageEnglish
Pages (from-to)D591-5
JournalNucleic Acids Research
Volume39
Issue numberDatabase issue
Publication statusPublished - Jan 2011

Keywords

  • Bacterial Proteins, Databases, Protein, Genome, Bacterial, Protein Sorting Signals, Protein Structure, Tertiary, Journal Article, Research Support, Non-U.S. Gov't