Economic evaluation of medical tests at the early phases of development: a systematic review of empirical studies

Research output: Contribution to journalArticlepeer-review

Standard

Harvard

APA

Vancouver

Author

Bibtex

@article{4c97a1cafa664f5b88d8ddcb2aebd14a,
title = "Economic evaluation of medical tests at the early phases of development: a systematic review of empirical studies",
abstract = "Background: There is little specific guidance on the implementation of cost-effectiveness modelling at the early stage of test development. The aim of this study was to review the literature in this field to examine the methodologies and tools that have been employed to date.Methods: A systematic review was conducted to identify relevant studies in established literature databases. Results: Five studies were identified and included for narrative synthesis. These studies revealed that there is no consistent approach in this growing field. The perspective of patients and the potential for value of information (VOI) to provide information on the value of future research is often overlooked. Test accuracy is an essential consideration, with most studies having described and included all possible test results in their analysis, and conducted extensive sensitivity analyses on important parameters. Headroom analysis was considered in some instances but at the early development stage (not the concept stage). Expert commentary: The techniques available to modellers that can demonstrate the value of conducting further research and product development (i.e. VOI analysis, headroom analysis) should be better utilized. There is the need for concerted efforts to develop rigorous methodology in this growing field to maximize the value and quality of such analysis. Key words: systematic review; methodologyVOI and Headroom analysis; early cost-effectiveness; economic evaluations; modelling; medical tests",
keywords = "systematic review, VOI and Headroom analysis, early cost-effectiveness, economic evaluations, modelling, medical tests",
author = "Samuel Frempong and Andrew Sutton and Clare Davenport and Pelham Barton",
year = "2018",
month = jan,
doi = "10.1080/14737167.2018.1411194",
language = "English",
volume = "18",
journal = "Expert Review of Pharmacoeconomics & Outcomes Research",
issn = "1473-7167",
publisher = "Informa Healthcare",
number = "1",

}

RIS

TY - JOUR

T1 - Economic evaluation of medical tests at the early phases of development

T2 - a systematic review of empirical studies

AU - Frempong, Samuel

AU - Sutton, Andrew

AU - Davenport, Clare

AU - Barton, Pelham

PY - 2018/1

Y1 - 2018/1

N2 - Background: There is little specific guidance on the implementation of cost-effectiveness modelling at the early stage of test development. The aim of this study was to review the literature in this field to examine the methodologies and tools that have been employed to date.Methods: A systematic review was conducted to identify relevant studies in established literature databases. Results: Five studies were identified and included for narrative synthesis. These studies revealed that there is no consistent approach in this growing field. The perspective of patients and the potential for value of information (VOI) to provide information on the value of future research is often overlooked. Test accuracy is an essential consideration, with most studies having described and included all possible test results in their analysis, and conducted extensive sensitivity analyses on important parameters. Headroom analysis was considered in some instances but at the early development stage (not the concept stage). Expert commentary: The techniques available to modellers that can demonstrate the value of conducting further research and product development (i.e. VOI analysis, headroom analysis) should be better utilized. There is the need for concerted efforts to develop rigorous methodology in this growing field to maximize the value and quality of such analysis. Key words: systematic review; methodologyVOI and Headroom analysis; early cost-effectiveness; economic evaluations; modelling; medical tests

AB - Background: There is little specific guidance on the implementation of cost-effectiveness modelling at the early stage of test development. The aim of this study was to review the literature in this field to examine the methodologies and tools that have been employed to date.Methods: A systematic review was conducted to identify relevant studies in established literature databases. Results: Five studies were identified and included for narrative synthesis. These studies revealed that there is no consistent approach in this growing field. The perspective of patients and the potential for value of information (VOI) to provide information on the value of future research is often overlooked. Test accuracy is an essential consideration, with most studies having described and included all possible test results in their analysis, and conducted extensive sensitivity analyses on important parameters. Headroom analysis was considered in some instances but at the early development stage (not the concept stage). Expert commentary: The techniques available to modellers that can demonstrate the value of conducting further research and product development (i.e. VOI analysis, headroom analysis) should be better utilized. There is the need for concerted efforts to develop rigorous methodology in this growing field to maximize the value and quality of such analysis. Key words: systematic review; methodologyVOI and Headroom analysis; early cost-effectiveness; economic evaluations; modelling; medical tests

KW - systematic review

KW - VOI and Headroom analysis

KW - early cost-effectiveness

KW - economic evaluations

KW - modelling

KW - medical tests

U2 - 10.1080/14737167.2018.1411194

DO - 10.1080/14737167.2018.1411194

M3 - Article

VL - 18

JO - Expert Review of Pharmacoeconomics & Outcomes Research

JF - Expert Review of Pharmacoeconomics & Outcomes Research

SN - 1473-7167

IS - 1

ER -