Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child

Research output: Contribution to journalArticle

Authors

  • Daouda Sissoko
  • Mory Keïta
  • Boubacar Diallo
  • Negar Aliabadi
  • David L Fitter
  • Benjamin A Dahl
  • Joseph Akoi Bore
  • Fara Raymond Koundouno
  • Katrin Singethan
  • Sarah Meisel
  • Theresa Enkirch
  • Antonio Mazzarelli
  • Victoria Amburgey
  • Ousmane Faye
  • Amadou Alpha Sall
  • N'Faly Magassouba
  • Miles W Carroll
  • Xavier Anglaret
  • Denis Malvy
  • Pierre Formenty
  • Raymond Bruce Aylward
  • Sakoba Keïta
  • Mamoudou Harouna Djingarey
  • Stephan Günther
  • Sophie Duraffour

Colleges, School and Institutes

External organisations

  • INSERM U1219, Bordeaux University, and.
  • World Health Organization, Conakry, Guinea.
  • Centers for Disease Control and Prevention, Atlanta, Georgia.
  • European Mobile Laboratory Consortium, Hamburg, Germany.
  • Sandia National Laboratories, Albuquerque, New Mexico.
  • Institut Pasteur, Dakar, Senegal.
  • Université Gamal Abdel Nasser de Conakry, Laboratoire des Fièvres Hémorragiques en Guinée, Conakry, Guinea.
  • World Health Organization, Geneva, Switzerland; and.
  • Ministry of Health, Conakry, Guinea.
  • Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, United Kingdom.
  • European Mobile Laboratory Consortium, Hamburg, Germany; sophieduraffour@yahoo.fr.

Abstract

A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.

Details

Original languageEnglish
JournalClinical Infectious Diseases
Early online date10 Dec 2016
Publication statusE-pub ahead of print - 10 Dec 2016