Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference

Larissa Fabritz; Harry J G M Crijns; Eduard Guasch; Andreas  Goette; Karl Hausler; Dipak Kotecha; Thorsten  Lewalter; Christian G Meyer; Tatjana S.  Potpara; Michiel  Rienstra; Renate B Schnabel; Stephan Willems; Guenter Breithardt; A John Camm; Anthony Chan; Winnie Wei Ling Chua; Mirko De Melis; Christina  Dimopoulou; Dobromir Dobrev; Christina Easter; Lars Eckardt; Doreen Haase; Stephane Hatem; Jeff S. Healey; Jordi  Heijman; Stefan H Hohnloser; Thomas Huebner; Bushra Saeed Ilyas; Aaron Isaacs; Ingo Kutschka; Christophe Leclercq; Gregory Lip; Elena Andreassi Marinelli; Jose L Merino; Lluis Mont; Michael Nabauer; Jonas Oldgren; Helmut Pürerfellner; Ursula Ravens; Irina Savelieva; Moritz F Sinner; Alice Sitch; Rudiger Smolnik; Jan Steffel; Kenneth Stein; Monika Stoll; Emma  Svennberg; Dierk Thomas; Isabelle C Van Gelder; Burcu Vardar; Reza Wakili; Mattias Wieloch; Stef Zeemering; Paul Ziegler; Hein Heidbuchel; Gerhard Hindricks; Ulrich Schotten; Paulus Kirchhof

doi:10.1093/europace/euaa279

Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference

Larissa Fabritz, Harry J G M Crijns, Eduard Guasch, Andreas Goette, Karl Hausler, Dipak Kotecha, Thorsten Lewalter, Christian G Meyer, Tatjana S. Potpara, Michiel Rienstra, Renate B Schnabel, Stephan Willems, Guenter Breithardt, A John Camm, Anthony Chan, Winnie Wei Ling Chua, Mirko De Melis, Christina Dimopoulou, Dobromir Dobrev, Christina EasterLars Eckardt, Doreen Haase, Stephane Hatem, Jeff S. Healey, Jordi Heijman, Stefan H Hohnloser, Thomas Huebner, Bushra Saeed Ilyas, Aaron Isaacs, Ingo Kutschka, Christophe Leclercq, Gregory Lip, Elena Andreassi Marinelli, Jose L Merino, Lluis Mont, Michael Nabauer, Jonas Oldgren, Helmut Pürerfellner, Ursula Ravens, Irina Savelieva, Moritz F Sinner, Alice Sitch, Rudiger Smolnik, Jan Steffel, Kenneth Stein, Monika Stoll, Emma Svennberg, Dierk Thomas, Isabelle C Van Gelder, Burcu Vardar, Reza Wakili, Mattias Wieloch, Stef Zeemering, Paul Ziegler, Hein Heidbuchel, Gerhard Hindricks, Ulrich Schotten, Paulus Kirchhof

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

AIMS: The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes. METHODS AND RESULTS: This article summarizes the outcomes of the 7th Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA) held in Lisbon in March 2019. Sixty-five international AF specialists met to present new data and find consensus on pressing issues in AF prevention, management and future research to improve care for patients with AF and prevent AF-related complications. This article is the main outcome of an interactive, iterative discussion between breakout specialist groups and the meeting plenary. AF patients have dynamic risk profiles requiring repeated assessment and risk-based therapy stratification to optimize quality of care. Interrogation of deeply phenotyped datasets with outcomes will lead to a better understanding of the cardiac and systemic effects of AF, interacting with comorbidities and predisposing factors, enabling stratified therapy. New proposals include an algorithm for the acute management of patients with AF and heart failure, a call for a refined, data-driven assessment of stroke risk, suggestions for anticoagulation use in special populations, and a call for rhythm control therapy selection based on risk of AF recurrence. CONCLUSION: The remaining morbidity and mortality in patients with AF needs better characterization. Likely drivers of the remaining AF-related problems are AF burden, potentially treatable by rhythm control therapy, and concomitant conditions, potentially treatable by treating these conditions. Identifying the drivers of AF-related complications holds promise for stratified therapy.

Original language	English
Pages (from-to)	329–344
Number of pages	16
Journal	EP Europace
Volume	23
Issue number	3
Early online date	29 Dec 2020
DOIs	https://doi.org/10.1093/europace/euaa279
Publication status	Published - Mar 2021

Bibliographical note

Publisher Copyright:
Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.

Funding Information:
The 7th AFNET/EHRA Consensus Conference was co-financed by AFNET and EHRA, and received additional financial support from the CATCH ME consortium (EU Horizon 2020 grant number 633196). Industry participants paid an attendance fee for the conference and provided an industry perspective during the discussions at the meeting but had no involvement in the writing process.

Publisher Copyright:
© 2020 Published on behalf of the European Society of Cardiology. All rights reserved.

Keywords

AFNET
Anticoagulation
Atrial cardiomyopathy
Atrial fibrillation
Big data
Bleeding
Catheter ablation
Cognitive function
Consensus statement
EHRA
Heart failure
Integrated care
Lifestyle
Outcomes
Quality of care
Rate control
Research
Research priorities
Rhythm control
Screening
Stroke
Technology

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

Access to Document

10.1093/europace/euaa279

Cite this

Fabritz, L., Crijns, H. J. G. M., Guasch, E., Goette, A., Hausler, K., Kotecha, D., Lewalter, T., Meyer, C. G., Potpara, T. S., Rienstra, M., B Schnabel, R., Willems, S., Breithardt, G., Camm, A. J., Chan, A., Chua, W. W. L., De Melis, M., Dimopoulou, C., Dobrev, D., ... Kirchhof, P. (2021). Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference. EP Europace, 23(3), 329–344. Advance online publication. https://doi.org/10.1093/europace/euaa279

@article{98c36e3a84e441879b4cb7803c46d785,

title = "Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference",

abstract = "AIMS: The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes. METHODS AND RESULTS: This article summarizes the outcomes of the 7th Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA) held in Lisbon in March 2019. Sixty-five international AF specialists met to present new data and find consensus on pressing issues in AF prevention, management and future research to improve care for patients with AF and prevent AF-related complications. This article is the main outcome of an interactive, iterative discussion between breakout specialist groups and the meeting plenary. AF patients have dynamic risk profiles requiring repeated assessment and risk-based therapy stratification to optimize quality of care. Interrogation of deeply phenotyped datasets with outcomes will lead to a better understanding of the cardiac and systemic effects of AF, interacting with comorbidities and predisposing factors, enabling stratified therapy. New proposals include an algorithm for the acute management of patients with AF and heart failure, a call for a refined, data-driven assessment of stroke risk, suggestions for anticoagulation use in special populations, and a call for rhythm control therapy selection based on risk of AF recurrence. CONCLUSION: The remaining morbidity and mortality in patients with AF needs better characterization. Likely drivers of the remaining AF-related problems are AF burden, potentially treatable by rhythm control therapy, and concomitant conditions, potentially treatable by treating these conditions. Identifying the drivers of AF-related complications holds promise for stratified therapy.",

keywords = "AFNET, Anticoagulation, Atrial cardiomyopathy, Atrial fibrillation, Big data, Bleeding, Catheter ablation, Cognitive function, Consensus statement, EHRA, Heart failure, Integrated care, Lifestyle, Outcomes, Quality of care, Rate control, Research, Research priorities, Rhythm control, Screening, Stroke, Technology",

author = "Larissa Fabritz and Crijns, {Harry J G M} and Eduard Guasch and Andreas Goette and Karl Hausler and Dipak Kotecha and Thorsten Lewalter and Meyer, {Christian G} and Potpara, {Tatjana S.} and Michiel Rienstra and {B Schnabel}, Renate and Stephan Willems and Guenter Breithardt and Camm, {A John} and Anthony Chan and Chua, {Winnie Wei Ling} and {De Melis}, Mirko and Christina Dimopoulou and Dobromir Dobrev and Christina Easter and Lars Eckardt and Doreen Haase and Stephane Hatem and Healey, {Jeff S.} and Jordi Heijman and Hohnloser, {Stefan H} and Thomas Huebner and {Saeed Ilyas}, Bushra and Aaron Isaacs and Ingo Kutschka and Christophe Leclercq and Gregory Lip and Marinelli, {Elena Andreassi} and Merino, {Jose L} and Lluis Mont and Michael Nabauer and Jonas Oldgren and Helmut P{\"u}rerfellner and Ursula Ravens and Irina Savelieva and Sinner, {Moritz F} and Alice Sitch and Rudiger Smolnik and Jan Steffel and Kenneth Stein and Monika Stoll and Emma Svennberg and Dierk Thomas and {Van Gelder}, {Isabelle C} and Burcu Vardar and Reza Wakili and Mattias Wieloch and Stef Zeemering and Paul Ziegler and Hein Heidbuchel and Gerhard Hindricks and Ulrich Schotten and Paulus Kirchhof",

note = "Publisher Copyright: Published on behalf of the European Society of Cardiology. All rights reserved. {\textcopyright} The Author(s) 2020. For permissions, please email: journals.permissions@oup.com. Funding Information: The 7th AFNET/EHRA Consensus Conference was co-financed by AFNET and EHRA, and received additional financial support from the CATCH ME consortium (EU Horizon 2020 grant number 633196). Industry participants paid an attendance fee for the conference and provided an industry perspective during the discussions at the meeting but had no involvement in the writing process. Publisher Copyright: {\textcopyright} 2020 Published on behalf of the European Society of Cardiology. All rights reserved.",

year = "2021",

month = mar,

doi = "10.1093/europace/euaa279",

language = "English",

volume = "23",

pages = "329–344",

journal = "EP Europace",

issn = "1099-5129",

publisher = "Oxford University Press",

number = "3",

}

Fabritz, L, Crijns, HJGM, Guasch, E, Goette, A, Hausler, K, Kotecha, D, Lewalter, T, Meyer, CG, Potpara, TS, Rienstra, M, B Schnabel, R, Willems, S, Breithardt, G, Camm, AJ, Chan, A, Chua, WWL, De Melis, M, Dimopoulou, C, Dobrev, D, Easter, C, Eckardt, L, Haase, D, Hatem, S, Healey, JS, Heijman, J, Hohnloser, SH, Huebner, T, Saeed Ilyas, B, Isaacs, A, Kutschka, I, Leclercq, C, Lip, G, Marinelli, EA, Merino, JL, Mont, L, Nabauer, M, Oldgren, J, Pürerfellner, H, Ravens, U, Savelieva, I, Sinner, MF, Sitch, A, Smolnik, R, Steffel, J, Stein, K, Stoll, M, Svennberg, E, Thomas, D, Van Gelder, IC, Vardar, B, Wakili, R, Wieloch, M, Zeemering, S, Ziegler, P, Heidbuchel, H, Hindricks, G, Schotten, U & Kirchhof, P 2021, 'Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference', EP Europace, vol. 23, no. 3, pp. 329–344. https://doi.org/10.1093/europace/euaa279

TY - JOUR

T1 - Dynamic risk assessment to improve quality of care in patients with atrial fibrillation

T2 - the 7th AFNET/EHRA Consensus Conference

AU - Fabritz, Larissa

AU - Crijns, Harry J G M

AU - Guasch, Eduard

AU - Goette, Andreas

AU - Hausler, Karl

AU - Kotecha, Dipak

AU - Lewalter, Thorsten

AU - Meyer, Christian G

AU - Potpara, Tatjana S.

AU - Rienstra, Michiel

AU - B Schnabel, Renate

AU - Willems, Stephan

AU - Breithardt, Guenter

AU - Camm, A John

AU - Chan, Anthony

AU - Chua, Winnie Wei Ling

AU - De Melis, Mirko

AU - Dimopoulou, Christina

AU - Dobrev, Dobromir

AU - Easter, Christina

AU - Eckardt, Lars

AU - Haase, Doreen

AU - Hatem, Stephane

AU - Healey, Jeff S.

AU - Heijman, Jordi

AU - Hohnloser, Stefan H

AU - Huebner, Thomas

AU - Saeed Ilyas, Bushra

AU - Isaacs, Aaron

AU - Kutschka, Ingo

AU - Leclercq, Christophe

AU - Lip, Gregory

AU - Marinelli, Elena Andreassi

AU - Merino, Jose L

AU - Mont, Lluis

AU - Nabauer, Michael

AU - Oldgren, Jonas

AU - Pürerfellner, Helmut

AU - Ravens, Ursula

AU - Savelieva, Irina

AU - Sinner, Moritz F

AU - Sitch, Alice

AU - Smolnik, Rudiger

AU - Steffel, Jan

AU - Stein, Kenneth

AU - Stoll, Monika

AU - Svennberg, Emma

AU - Thomas, Dierk

AU - Van Gelder, Isabelle C

AU - Vardar, Burcu

AU - Wakili, Reza

AU - Wieloch, Mattias

AU - Zeemering, Stef

AU - Ziegler, Paul

AU - Heidbuchel, Hein

AU - Hindricks, Gerhard

AU - Schotten, Ulrich

AU - Kirchhof, Paulus

N1 - Publisher Copyright: Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com. Funding Information: The 7th AFNET/EHRA Consensus Conference was co-financed by AFNET and EHRA, and received additional financial support from the CATCH ME consortium (EU Horizon 2020 grant number 633196). Industry participants paid an attendance fee for the conference and provided an industry perspective during the discussions at the meeting but had no involvement in the writing process. Publisher Copyright: © 2020 Published on behalf of the European Society of Cardiology. All rights reserved.

PY - 2021/3

Y1 - 2021/3

N2 - AIMS: The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes. METHODS AND RESULTS: This article summarizes the outcomes of the 7th Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA) held in Lisbon in March 2019. Sixty-five international AF specialists met to present new data and find consensus on pressing issues in AF prevention, management and future research to improve care for patients with AF and prevent AF-related complications. This article is the main outcome of an interactive, iterative discussion between breakout specialist groups and the meeting plenary. AF patients have dynamic risk profiles requiring repeated assessment and risk-based therapy stratification to optimize quality of care. Interrogation of deeply phenotyped datasets with outcomes will lead to a better understanding of the cardiac and systemic effects of AF, interacting with comorbidities and predisposing factors, enabling stratified therapy. New proposals include an algorithm for the acute management of patients with AF and heart failure, a call for a refined, data-driven assessment of stroke risk, suggestions for anticoagulation use in special populations, and a call for rhythm control therapy selection based on risk of AF recurrence. CONCLUSION: The remaining morbidity and mortality in patients with AF needs better characterization. Likely drivers of the remaining AF-related problems are AF burden, potentially treatable by rhythm control therapy, and concomitant conditions, potentially treatable by treating these conditions. Identifying the drivers of AF-related complications holds promise for stratified therapy.

AB - AIMS: The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes. METHODS AND RESULTS: This article summarizes the outcomes of the 7th Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA) held in Lisbon in March 2019. Sixty-five international AF specialists met to present new data and find consensus on pressing issues in AF prevention, management and future research to improve care for patients with AF and prevent AF-related complications. This article is the main outcome of an interactive, iterative discussion between breakout specialist groups and the meeting plenary. AF patients have dynamic risk profiles requiring repeated assessment and risk-based therapy stratification to optimize quality of care. Interrogation of deeply phenotyped datasets with outcomes will lead to a better understanding of the cardiac and systemic effects of AF, interacting with comorbidities and predisposing factors, enabling stratified therapy. New proposals include an algorithm for the acute management of patients with AF and heart failure, a call for a refined, data-driven assessment of stroke risk, suggestions for anticoagulation use in special populations, and a call for rhythm control therapy selection based on risk of AF recurrence. CONCLUSION: The remaining morbidity and mortality in patients with AF needs better characterization. Likely drivers of the remaining AF-related problems are AF burden, potentially treatable by rhythm control therapy, and concomitant conditions, potentially treatable by treating these conditions. Identifying the drivers of AF-related complications holds promise for stratified therapy.

KW - AFNET

KW - Anticoagulation

KW - Atrial cardiomyopathy

KW - Atrial fibrillation

KW - Big data

KW - Bleeding

KW - Catheter ablation

KW - Cognitive function

KW - Consensus statement

KW - EHRA

KW - Heart failure

KW - Integrated care

KW - Lifestyle

KW - Outcomes

KW - Quality of care

KW - Rate control

KW - Research

KW - Research priorities

KW - Rhythm control

KW - Screening

KW - Stroke

KW - Technology

UR - http://www.scopus.com/inward/record.url?scp=85102905879&partnerID=8YFLogxK

U2 - 10.1093/europace/euaa279

DO - 10.1093/europace/euaa279

M3 - Article

SN - 1099-5129

VL - 23

SP - 329

EP - 344

JO - EP Europace

JF - EP Europace

IS - 3

ER -

Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this