Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: implications for non-Hodgkin’s lymphoma

Elisabeth Meredith; Michelle Holder; A Rosen; A Drake Lee; MJ Dyer; Nicholas Barnes; John Gordon

doi:10.1073/pnas.0605993103

Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: implications for non-Hodgkin’s lymphoma

Elisabeth Meredith, Michelle Holder, A Rosen, A Drake Lee, MJ Dyer, Nicholas Barnes, John Gordon

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48 Citations (Scopus)

Abstract

Human B lymphocytes and derived lines from a spectrum of 8 cell malignancy were studied for expression of dopaminergic pathway components and for their cytostatic response to the catecholamine and related, potentially therapeutic compounds. Proliferating normal lymphocytes and dividing malignant clones rapidly arrested on exposure to dopamine in the low (

Original language	English
Pages (from-to)	13485-90
Number of pages	6
Journal	National Academy of Sciences. Proceedings
Volume	103
Issue number	36
DOIs	https://doi.org/10.1073/pnas.0605993103
Publication status	Published - 8 Aug 2006

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abstract = "Human B lymphocytes and derived lines from a spectrum of 8 cell malignancy were studied for expression of dopaminergic pathway components and for their cytostatic response to the catecholamine and related, potentially therapeutic compounds. Proliferating normal lymphocytes and dividing malignant clones rapidly arrested on exposure to dopamine in the low (",

author = "Elisabeth Meredith and Michelle Holder and A Rosen and {Drake Lee}, A and MJ Dyer and Nicholas Barnes and John Gordon",

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AU - Holder, Michelle

AU - Rosen, A

AU - Drake Lee, A

AU - Dyer, MJ

AU - Barnes, Nicholas

AU - Gordon, John

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DO - 10.1073/pnas.0605993103

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EP - 13490

JO - National Academy of Sciences. Proceedings

JF - National Academy of Sciences. Proceedings

IS - 36

ER -

Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: implications for non-Hodgkin’s lymphoma

Abstract

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